Buradasınız

Son Dönem Böbrek Yetmezliği Olan Hastalarda Sol Ventrikül Sistolik ve Diyastolik İşlevleri Üzerine Periton Diyalizinin Etkisi

Effect of Peritoneal Dialysis Treatment on Left Ventricular Systolic and Diastolic Functions in Patients with End-Stage Renal Disease

Journal Name:

Publication Year:

DOI: 
10.5262/tndt.2014.1003.05
Abstract (2. Language): 
OBJECT IVE : To analyze the effect of peritoneal dialysis (PD) treatment on left ventricular systolic and diastolic function in patients with end-stage renal disease (ESRD). MATER IAL and METH ODS: The study population consisted of 51 patients with ESRD. Before a PD catheter was inserted, the patients were evaluated by echocardiography and Doppler tissue imaging (DTI). Then, a PD catheter was inserted. After 6 months, the second echocardiographic evaluations were performed. Left ventricular systolic and diastolic function parameters were compared. RE SULT S: The mean age was 47 ± 13 years and 38 (74.5%) of the patients were male. No significant difference was found in echocardiographic parameters including ejection fraction, fractional shortening, left ventricular mass, left ventricular mass index, left ventricular posterior wall thickness, inter ventricular septal thickness, left atrial diameter, early diastolic filling/late diastolic filling ratio before and after the period of PD. Left ventricular end-systolic diameter and left ventricular end-diastolic diameter values were significantly lower found in the period after PD. CONCLU SION: Our findings appear to reflect somewhat the favourable changes in LV diastolic and systolic functions in PD patients.
Abstract (Original Language): 
AMAÇ: Çalışmanın amacı, son dönem böbrek yetmezliği (SDBY) olan hastalarda sol ventrikül sistolik ve diyastolik fonksiyonlar üzerine periton diyalizi (PD) tedavisinin etkisini değerlendirmekti. GEREÇ ve YÖNTE MLER : Çalışmaya SDBY olan 51 hasta alındı. PD kateteri takılmadan önce, hastalar ekokardiyografi ve doku Doppler görüntüleme (DDG) ile değerlendirildi. Daha sonra PD kateteri takıldı. Altı ay sonra ikinci bir ekokardiyografik inceleme daha yapıldı. Sol ventrikülün sistolik ve diyastolik işlevleri karşılaştırıldı. BULGUL AR: Hastaların ortalama yaşı 47 ± 13 yıldı ve hastaların 38 (%74,5) tanesi erkekti. PD başlamadan önce ve PD başlandıktan 6 ay sonra bakılan ejeksiyon fraksiyonu, fraksiyonel kısalma, sol ventrikül kitlesi, sol ventrikül kitle indeksi, sol ventrikül arka duvar kalınlığı, ventriküller arası septum kalınlığı, sol atrium çapı, erken diyastolik dolum/geç diyastolik dolum oranını içeren ekokardiyografik parametreler açısından anlamlı fark saptanmadı. Sol ventrikül sistol sonu çapı ve sol ventrikül diyastol sonu çapı PD sonrası dönemde anlamlı olarak daha düşüktü. SONUÇ : Bizim bulgularımız PD hastalarında sol ventrikül diyastolik ve sistolik fonksiyonlarda bir miktar olumlu değişikliğin olduğunu yansıtır gibi görünmektedir.
202
209

REFERENCES

References: 

1. Jardine AG, McLaughlin K: Cardiovascular complications of renal
disease. Heart 2001; 86:459-466
2. Schärer K, Schmidt KG, Soergel M: Cardiac function and structure
in patients with chronic renal failure. Pediatr Nephrol 1999; 13:
951-965
3. Chen SC, Chang JM, Liu WC, Huang JC, Tsai JC, Lin MY, Su
HM, Hwang SJ, Chen HC: Echocardiographic parameters are
independently associated with increased cardiovascular events in
patients with chronic kidney disease. Nephrol Dial Transplant 2012;
27:1064-1070
4. Scharer K, Schmidt KG, Soergel M: Cardiac function and structure
in patients with chronic renal failure. Pediatr Nephrol 1999; 13:951-
965
5. Mitsnefes MM, Daniels SR, Schwartz SM, Meyer RA, Khoury P,
Strife CF: Severe left ventricular hypertrophy in pediatric dialysis:
Prevalence and predictors. Pediatr Nephrol 2000; 14:898-902
6. London G: Pathophysiology of cardiovascular damage in the early
renal population. Nephrol Dial Transplant 2001; 16:3-6
7. Hüting J, Alpert MA: Progression of left ventricular hypertrophy in
end-stage renal disease treated by continuous ambulatory peritoneal
dialysis depends on hypertension end hypercirculation. Clin Cardiol
1992; 15:190-196
8. Unal A, Sipahioglu M, Oguz F, Kaya M, Kucuk H, Tokgoz B,
Buyukoglan H, Oymak O, Utas C: Pulmonary hypertension in
peritoneal dialysis patients: Prevalence and risk factors. Perit Dial
Int 2009; 29:191-198
9. Duran M, Unal A, Inanc MT, Kocyigit I, Oguz F, Ocak A, Ozdogru İ,
Kasapkara A, Karakaya E, Oymak O: Hemodialysis does not impair
ventricular functions over 2 years. Hemodial Int 2011; 15:334-340
10. Devereux RB, Lutas EM, Casale PN, Kligfield P, Eisenberg RR,
Hammond IW, Miller DH, Reis G, Alderman MH, Laragh JH:
Standardization of M-mode echocardiographic left ventricular
anatomic measurements. J Am Coll Cardiol 1984; 4:1222-1230
11. Teichholz LE, Kreulen T, Herman MV, Gorlin R: Problems in
echocardiographic volume determinations: Echocardiographicangiographic
correlations in the presence of absence of asynergy.
Am J Cardiol 1976; 37:7-11
209
Türk Nefroloji Diyaliz ve Transplantasyon Dergisi
Turkish Nephrology, Dialysis and Transplantation Journal Kavuncuoğlu F et al : PD and Left Ventricular Functions
Turk Neph Dial Transpl 2014; 23 (3): 202-209
12. Devereux RB, Wachtell K, Gerdts E, Boman K, Nieminen MS,
Papademetriou V, Rokkedal J, Harris K, Aurup P, Dahlöf B:
Prognostic significance of left ventricular mass change during
treatment of hypertension. JAMA 2004; 292:2350-2356
13. Foley RN, Parfrey PS, Kent GM, Harnett JD, Murray DC, Barre PE:
Serial change in echocardiographic parameters and cardiac failure
in end-stage renal disease. J Am Soc Nephrol 2000; 11:912-916
14. Foley RN, Parfrey PS, Sarnak MJ: Epidemiology of cardiovascular
disease in chronic renal disease. J Am Soc Nephrol 1998; 9(12
Suppl):S16-S23
15. Best PJ, Holmes DR: Chronic kidney disease as a cardiovascular
risk factor. Am Heart J 2003; 145:383-386
16. Knight EL, Rimm EB, Pai JK, Rexrode KM, Cannuscio CC, Manson
JE, Stampfer MJ, Curhan GC: Kidney dysfunction, inflammation,
and coronary events: A prospective study. J Am Soc Nephrol 2004;
15:1897-1903
17. Silberberg JS, Barre PE, Prichard SS, Sniderman AD: Impact of
left ventricular hypertrophy on survival in end stage renal failure.
Kidney Int 1989; 36:286-290
18. Koç M, Toprak A, Tezcan H, Bihorac A, Akoglu E, Ozener IC:
Uncontrolled hypertension due to volume overload contributes to
higher left ventricular mass index in CAPD patients. Nephrol Dial
Transplant 2002; 17:1661-1666
19. Tian JP, Wang T, Wang H, Cheng LT, Tian XK, Lindholm B,
Axelsson J, Du FH: The prevalence of left ventricular hypertrophy
in Chinese hemodialysis patients is higher than that in peritoneal
dialysis patients. Ren Fail 2008; 30:391-400
20. Glassock RJ, Pecoits-Filho R, Barberato SH: Left ventricular mass
in chronic kidney disease and ESRD. Clin J Am Soc Nephrol 2009;
4 (Suppl 1):S79-91
21. Feigenbaum H, Armstrong WF, Ryan T: Evaluation of systolic
and diastolic functions of the left ventricle. In: Feigenbaum H,
Armstrong WF, Ryan T (eds), Feigenbaum’s Echocardiography. 6th
ed. Philadelphia: Lippincott Williams & Wilkins, 2005;138-180
22. Foley RN, Parfrey PS, Harnett JD, Kent GM, Murray DC, Barre PE:
The prognostic importance of left ventricular geometry in uremic
cardiomyopathy. J Am Soc Nephrol 1995; 5:2024-2031
23. Waggoner AD, Bierig SM: Tissue Doppler imaging: A useful
echocardiographic method for the cardiac sonographer to assess
systolic and diastolic ventricular function. J Am Soc Echocardiogr
2001; 14:1143-1152
24. Oğuzhan A, Arınc H, Abaci A, Topsakal R, Kemal Eryol N,
Ozdoğru I, Basar E, Ergin A: Preload dependence of Doppler
tissue imaging derived indexes of left ventricular diastolic function.
Echocardiography 2005; 22:320-325
25. Kimura H, Takeda K, Tsuruya K, Mukai H, Muto Y, Okuda H,
Furusho M, Ueno T, Nakashita S, Miura S, Maeda A, Kondo H: Left
ventricular mass index is an independent determinant of diastolic
dysfunction in patients on chronic hemodialysis: A tissue Doppler
imaging study. Nephron Clin Pract 2011; 117:c67-c73
26. Raizada V, Skipper B, Taylor RA, Luo W, Harford AA, Zager PG,
Rohrscheib M, Spalding CT: Left ventricular diastolic function in
patients on hemodialysis. J Investig Med 2010; 58:791-795
27. Hacıömeroğlu P, Özkaya O, Günal N, Baysal K: An
echocardiographic assessment of cardiac functions and structure in
children on dialysis. Renal Failure 2008; 30:147-153
28. Uçar T, Tutar E, Yalçinkaya F, Cakar N, Ozçakar ZB, Atalay S,
Uncu N, Kara N, Ekim M: Global left-ventricular function by tissue
Doppler imaging in pediatric dialysis patients. Pediatr Nephrol
2008; 23:779-785
29. Çivilibal M, Çalışkan S, Oflaz H, Sever L, Candan C, Canpolat N,
Kasapcopur O, Arisoy N: Left ventricular function by ‘conventional’
and ‘Tissue Doppler’ echocardiography in paediatric dialysis
patients. Nephrology 2009; 14:636-642
30. Fathi R, Isbel N, Haluska B, Case C, Johnson DW, Marwick TH:
Correlates of subclinical left ventricular dysfunction in ESRD. Am
J Kidney Dis 2003; 41:1016-1025
31. Appleton CP, Galloway JM, Gonzalez MS, Gaballa M, Basnight
MA: Estimation of left ventricular filling pressures using twodimensional
and Doppler echocardiography in adult patients with
cardiac disease. Additional value of analyzing left atrial size, left
atrial ejection fraction and the difference in duration of pulmonary
venous and mitral flow velocity at atrial contraction. J Am Coll
Cardiol 1993; 22:1972-1982
32. Barberato SH, Mantilla DE, Misocami MA, Gonçalves SM, Bignelli
AT, Riella MC, Pecoits-Filho R: Effect of preload reduction by
hemodialysis on left atrial volume and echocardiographic Doppler
parameters in patients with end-stage renal disease. Am J Cardiol
2004; 94:1208-1210
33. Alpert MA: Cardiac performance and morphology in end-stage
renal disease. Am J Med Sci 2003; 325:168-178
34. Meeus F, Kourilsky O, Guerin AP, Gaudry C, Marchais SJ, London
GM: Pathophysiology of cardiac disease in hemodialysis patients.
Kidney Int Suppl 2000; 76:S140-S147

Thank you for copying data from http://www.arastirmax.com