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KRONİK BÖBREK YETMEZLÎKLÎ ÇOCUKLARDA KARDÎYOVASKÜLER SİSTEM KOMPLÎKASYONLARININ DEĞERLENDİRİLMESİ

ASSESSMENT OF CARDIAC COMPLICATIONS IN CHILDREN WITH CHRONIC RENAL FAILURE

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Abstract (2. Language): 
Cardiac complications are the major cause of mortality in children with chronic renal failure (CRF). Fifty children with CRF (23 female and 27 male; aged 12,3+3,6 years, range 5 to 20 years) were assessed to determine the prevalence of cardiac changes. Complete blood count, 12-lead electrocardiogram (ECG), telecardiogram, and echocardiography were performed in all children. Eight patients were on hemodialysis, 28 were on continuous ambulatory peritoneal dialysis, and 14 were predialysis patients. Thirty-four children (% 68) had an increased cardiothoracic ratio on radiography. When compared with the control group, patients with CRF had greater QT/QTc intervals and QT/QTc dispersion values. Twenty-two children had left ventricular hypertrophy according to ECG findings. On echocardiography 23 children had left ventricular dilatation and 27 had left ventricular hypertrophy. Abnormal left ventricular systolic function was found in 16 of 50 children. Twelwe children had mitral regurgitation, 9 had tricuspid regurgitation and 3 had aortic regurgitation. Nine children had pericardial effusion. In conclusion, children with CRF have significant cardiac abnormalities that are likely to contribute to the high cardiovascular morbidity and mortality.
Abstract (Original Language): 
Kardiyovasküler sistem komplikasy onları kronik böbrek yetmezlikti (KBY) çocuklarda mortalitenin en önemli nedenidir. Bu çalışmada KBYli 50 çocukta kardiyak bulguların araştırılması planlanmıştır. Bu amaçla tüm hastalara fizik inceleme, tam kan sayımı, elektrokardiyografi (EKG), telekardiyografik ve ekokardiyografık inceleme yapıldı. Çalışmaya yaşları 5 ile 20 yıl (ort. 12,3±3,6 yıl) arasında değişen 23 kız ve 27 erkek hasta alındı. Hastaların 8i hemodiyaliz, 28i sürekli ambulatuar periton diyalizi ve 14'ii prediyaliz hastasıydı. Telekardiyografide 34 hastada (% 68) kardiyomegali saptandı. Elektrokardiyografi değerlendirmede QT/QTc intervali ve QT/QTc dispersiyonunun artmış olduğu ve 22 hastada (% 44) sol ventrikül hipertrofisi bulgularının eşlik ettiği görüldü. Ekokardiyografık değerlendirmede 23 hastada (% 46) sol ventrikül diyastol ve sistol sonu çaplarının arttığı, 27 hastada (% 54) sol ventrikülde hipertrofi olduğu görüldü. Sol ventrikül sistolik fonksiyonları 16 hastada (% 32) azalmış bulundu. Oniki hastada mitral yetmezliği, 9 hastada triküspit yetmezliği ve 3 hastada aort yetmezliği görüldü. Perikardiyal efuzyon hastaların % 18 'inde saptandı. Sonuç olarak hastalarımızın önemli bir kısmında kardiyak morbidite ve mortaliteye neden olabilecek kardiyak komplikasyonların geliştiği gösterildi
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