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AKUT RENAL YETMEZLİK

ACUTE RENAL FAILURE

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Abstract (2. Language): 
Acute renal failure is defined as the abrupt decline in glomeruler filtration rate resulting from ischemic or toxic injury and observed mostly in the critical care units. The most important factors playing role in the initiation and maintenance of acute renal failure according to recent data are decrease of glomerular capillary permeability, back-leak of glomerular filtrate, tubular obstruction and intra renal vasoconstriction. If we know the pathogenesis of this injury; therapeutic maneuvers can be easily targeted to restore renal functions.
Abstract (Original Language): 
Akut renal yetmezlik sıklıkla yoğun bakım ünitesi hastalarında toksik ya da iskemik zararlanmaya bağlı olarak glomerül filtrasyon hızında ani düşüşle seyreden klinik tablo olarak tanımlanır. Son bilgiler akut renal yetmezlik gelişiminde rol oynayan faktörlerin glomerüler kapiller geçirgenlikte azalma, glomerül fıltratında geri akım, tübüler tıkanma ve intrarenal vasokonstriksiyon olduğunu söylemektedir. Bu patogenetik mekanizmaları bilmemiz renal fonksiyonların düzeltilmesini hedefleyen tedavi yaklaşımları geliştirmemize yardım edecektir.
FULL TEXT (PDF): 
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REFERENCES

References: 

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