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AKUT BÖBREK YETMEZLÎKLÎ HASTALARDA RENÎN-ANJÎOTENSÎN SÎSTEMÎNÎN BLOKAJININ RENAL HEMODÎNAMÎ ÜZERÎNE ETKÎSÎNÎN DOPPLER ULTRASONOGRAFÎ ÎLE DEĞERLENDÎRÎLMESÎ

THE EFFECT OF RENÎN-ANGIONTENSÎN SYSTEM BLOCKAGE ON RENAL HEMODYNAMICS IN PATIENTS WÎTH ACUTE RENAL FAILURE: EVALUATION BY DOPPLER ULTRASONOGRAPHY

Journal Name:

  • Türk Nefroloji, Diyaliz ve Transplantasyon Dergisi

Publication Year:

  • 1995

Key Words:

Keywords (Original Language):

Author NameUniversity of AuthorFaculty of Author
Abstract (2. Language): 
The purpose of this study was to determine the ef¬fect of angiotensin-converting enzyme inhibitor (Cap-topril) on renal hemodynamics in patients with acute renal failure (ARF). The resistive index (RI) value was calculated by Doppler ultrasonography before and after oral Captopril treatment in 11 patients with ARF and 11 healthy subjects. The mean RI value was found to be significantly higher in patients with ARF (0.75 ±0.07) than those in the control group (0.55 ± 0.04) (p< 0.05). After Captopril, treatment the mean RI value was significantly decreased in patients with ARF (p< 0.05), but was not changed in the control group (p> 0.05). We concluded that the renin-angio-tensin system inhibition may have a benefical effect on renal hemodynamics in patients with ARF.,
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Abstract (Original Language): 
Bu çalışmanın amacı, akut böbrek yetmezlikti (ABY) hastalarda bir anjiotensin-konverting enzim in-hibitörü olan Kaptoprilin renal hemodinami üzerine olan etkisinin araştırılmasıdır. Bu amaçla, 11 ABY'li hasta ile 11 sağlıklı kişide oral yoldan Kaptopril ve¬rilmesinden önce ve sonra Doppler ultasonografi ile intrarenal rezistivite indeks (RI) değeri hesaplandı. Akut böbrek yetmezlikti hastalarda ortalama RI değe¬ri (0.75 ± 0.07) kontrol grubundan (0.55 ± 0.04) an¬lamlı olarak yüksek bulundu (p<0.05). Kaptopril'den sonra, ortalama RI değeri ABY'li olgularda anlamlı olarak azalırken (p< 0.05), kontrol grubunda değişik¬lik göstermedi (p> 0.05). Sonuçta, ABY'li hastalarda renin-anjiotensin sisteminin inhibisyonunun renal he-modinami üzerine yararlı etkisi olabileceği kanısına varıldı.
FULL TEXT (PDF): 
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  • 3
168-171
  • Turkish

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