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Optimization of Carotenoids Production from Rhototorula Rubra Using Central Composite Design

Journal Name:

  • International Journal of Science and Engineering Investigations

Publication Year:

  • 2012

Key Words:

Author Name
Abstract (2. Language): 
The red yeast, Rhodotorula rubra produced 161 μg/g cell dry weight of carotenoids with 15.0 g glucose, 2.0 g (NH4)2SO4, 1.0 g yeast extract (YE), pH 5.5, and 37 0C. (per litre). The carbon source (glucose ; c), nitrogen source (ammonium sulfate ; n), growth factor (yeast extract ; GF), pH and temperature (TEMP) were the factors affected on improving carotenoids production. The optimization was predicted the best condition for carotenoids production using central composite design and quadratic model analysis. The predicted maximum carotenoid of 259.14 μg/g cell dry weight could be estimated at 23.77 g glucose, 3.19 g (NH4)2SO4, 3.19 g yeast extract (YE), pH 6.69, and 37.13 0C (per litre)., while that was 235.84 μg/g cell dry weight in practical.
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  • 8
72-75
  • English

REFERENCES

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