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A STUDY ON ANTIBACTERIAL PROPERTIES OF TINOSPORA CORDIFOLIA LEAF, STEM, ROOT EXTRACTS

Journal Name:

  • The International Journal of Pharmaceutical Research and Bio-Science

Publication Year:

  • 2012

Key Words:

Author Name
Abstract (2. Language): 
Water (at room temperature and at elevated temperature), 70% ethanol, 80 % methanol, acetone, ethyl acetate and chloroform extracts of Tinospora cordifolia (Giloy) in a final concentration of 100 mg/ml were evaluated for their antibacterial properties against bacterial pathogens such as Escherichia coli, staphylococcus aureus and Pseudomonas aeruginosa using agar well diffusion method. Water (at room temperature and at elevated temperature), ethanolic and ethyl acetate extracts of Tinospora leaves showed an average inhibitory zone of 14mm, 14.5mm, 17mm and 12.5mm respectively which indicates that ethanolic extract shows best result having zone of inhibition more than that of tetracycline (12mm against all pathogens) while extracts of methanol, acetone and chloroform didn't show any result. In case of Tinospora stem and root best result was shown by hot aqueous extract with a zone of inhibition of 16mm and 17mm respectively. The ethanolic extract of root also gave a zone of 17mm.
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FULL TEXT (PDF): 
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  • 6
291-298
  • English

REFERENCES

References: 

1. Upadhyay AK, Kumar A and Mishra HS: Tinospora cordifolia (Willd.) Hook. F. and Thoms. (Guduchi) - Validation of the Ayurvedic pharmacology through experimental and clinical studies. Int J Ayurveda Res. 2010; 1(2): 112-121.
2. Sharma A, Gupta A, Singh S and Batra A: Tinospora cordifolia (Willd.) Hook. F. &
Thomson - A plant with immense economic potential. J. Chem. Pharm. Res. 2010; 2(5):
327-333.
3. Uddin MH, Hossain MA, and Kawsar MH: Antimicrobial and cytotoxic activities of Tinospora cordifolia (FAM:
Menispermaceae), IJPSR. 2011; 2(3): 656¬658.
Available Online At www.ijprbs.com
Research Article
Khan JA, IJPRBS, 2012; Volume 1(6): 291-298
4. Singh SS, Pandey SC, Srivastava S, Gupta VS, Patro B and Ghosh AC: Chemistry and medicinal properties of Tinospora cordifolia (Guduchi). Indian Journal of Pharmacology. 2002; 35: 83-91.
5. Rose MF, Noorulla KM, Asma M, Kalaichelvi R, Thangabalan KVB and Sinha BN: Invitro antibacterial activity of methanolic root extract of Tinospora cordifolia (willd). IJPRD/2010/PUB/ARTI/VOV-2. 2007.
6. Sankhala LN, Saini RK and Saini BS: A review on chemical and biological properties on Tinospora cordifolia. Int. J. Med. Arom Plants, 2012.
7. Jeyachandran R, Xavier TF and Anand SP: Antibacterial activity of stem extracts of Tinospora cordifolia (willd) hook. F & Thomson. Ancient Science of Life. 2003;
XXIII (1).
ISSN: 2277-8713
IJPRBS
8. Aher VD and Wahi AK. 2010.
Pharmacological Study of Tinospora Cordifolia as an Immunomodulator, International Journal of Current Pharmaceutical Research. 2010; 2(4).
9. Raoof KMA and Siddiqui MB: Allelopathic effect of aqueous extracts of different parts of Tinospora cordifolia (Willd.) Miers on some weed plants. Journal of Agricultural Extension and Rural Development. 2012;
4(6), 115-119.
10. Ranjith MS, Ranjitsingh AJA, Shankar SG, Vijayalaksmi GS, Deepa K and Sidhu HS: Enhanced Phagocytosis and Antibody Production by Tinospora cordifolia - A new dimension in Immunomodulation. African Journal of Biotechnology. 2007; 7 (2), 081¬085.

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