Electrophysiology Activity of the Photoreceptors Using Photopic Adapted Full-Field Electroretinogram in Young Malay Adults

Journal Name:

Publication Year:

Abstract (2. Language): 
The full-field electroretinogram (ffERG) was used as an electrophysiological test of retinal function. The electrophysiology activity of the photoreceptors in the retina was investigated using photopic adapted full-field electroretinogram (ffERG) in a sample of Malay ethnic (Melayu), (mean 21.72 ± 0.88 years old). About 10 minutes room illumination of photopic adaptation was used, single flashes of 3 cd.s.m-2 presented until 4 similar artifact free ERG waveforms, and 30 Hz flickers ERG was averaged based on 15 sweeps of 250 milliseconds (ms) duration, which based on the International Society of Clinical Electrophysiology of Vision (ISCEV) 2008 ERG Standard. The mean, standard deviation and median of amplitude (μV) of cone a-wave (-30.73 ± 12.49, -29.22) and cone b-wave (119.26 ± 37.76, 119.45), and the latency time (ms) of cone a-wave (14.30 ± 1.15, 14.50) and cone b-wave (30.02 ± 0.98, 30.00), 30 Hz peak amplitude (97.12 ± 28.63, 86.51), and latency time for peak (26.27 ± 1.77, 26.00) and trough (13.13 ± 2.10, 13.00) respectively were shown in descriptive data. The normal value of young Malay adults as the baseline data for Malay population and comparable to other population around the world is important for ffERG practical.



[1] M. Marmor, G. Arden, S. Nilsson, and E. Zrenner, “Standard for clinical electroretinography: International
standardization committee,” Archives of Ophthalmology, vol. 107, no. 6, 1989.
[2] M. Marmor, A. Fulton, G. Holder, Y. Miyaki, M. Brigell, and M. Bach, “ISCEV Standard for full-field clinical
electroretinography (2008 update),” Doc Ophthalmol., vol. 118, no. 1, pp. 69-77, 2009.
[3] A. Collins, Security and Southeast Asia: domestic, regional, and global issues. Institute of Southeast Asian Studies, 2003.
[4] N. J. Ryan, A history of Malaysia and Singapore. Oxford University Press, 1976, p. 322.
[5] HUGO, “Mapping Human Genetic Diversity in Asia,” vol. 326, no. 5959, pp. 1541-5, 2009. doi: 10.1126/science.1177074
[6] BBC News, “Genetic ‘map’ of Asia’s diversity,” no. November, 2009.
[7] A. Al Abdlseaed, Y. McTaggart, T. Ramage, R. Hamilton, and D. L. McCulloch, “Light- and dark-adapted
electroretinograms (ERGs) and ocular pigmentation: comparison of brown- and blue-eyed cohorts.,” Documenta
ophthalmologica. Advances in ophthalmology, vol. 121, no. 2, pp. 135–46, Oct. 2010.
[8] A. B. Fulton, R. M. Hansen, and C. a Westall, “Development of ERG responses: the ISCEV rod, maximal and cone
responses in normal subjects.,” Documenta ophthalmologica. Advances in ophthalmology, vol. 107, no. 3, pp. 235–41,
Nov. 2003.
[9] R. Karanjia, M. W. Hove, and S. G. Coupland, Electroretinograms and Normative Data. In: Gregor Belusic,
Electroretinograms, InTech, 2007. DOI: 10.5772/23387

Thank you for copying data from http://www.arastirmax.com