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A Comparative Study of use of fibrin glue and vicryl suture in conjunctival autograft transplantation following Pterygium Excision

Journal Name:

  • Indian Journal of Basic & Applied Medical Research

Publication Year:

  • 2014
Author Name
Abstract (2. Language): 
Introduction: Use of sutures for securing conjunctival autograft following pterygium excision has several drawbacks. We aimed to compare the use of 8-0 Vicryl sutures versus fibrin glue for fixating conjunctival autografts in patients undergoing pterygium surgery. Materials and Methods : A prospective interventional clinical study was carried out in a tertiary eye hospital. Sixty patients (60 eyes) with primary pterygium were randomised to undergo pterygium surgery using either 8-0 Vicryl sutures (30 eyes) or fibrin glue (30 eyes) to attach the conjunctival autograft. The patients were followed up for 12 months. Outcome measures were duration of surgery, complication, post-operative discomfort and recurrence of pterygium. Observations and Results : In the suture group, the mean operation time was 34.3 min (range 30-41 min) and in the fibrin glue group it was 13.13 min (range 11-17 min) {p <0.001}. Post-operative discomfort was significantly lower in the fibrin glue group than in the suture group (p <0.001). The incidence of complications were similar in both groups (4 each). At the end of follow-up, pterygium recurrence was observed in one eye (3.33%) in the fibrin glue group and in three eyes (10%) in the suture group (p <0.05). Conclusion : Application of fibrin glue instead of sutures for attaching the free conjunctival graft in pterygium surgery resulted in shorter surgical time, less post-operative discomfort and lower recurrence.
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Indian Journal of Basic and Applied Medical Research; December 2014: Vol.-4, Issue- 1, P. 169-175
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www.ijbamr.com P ISSN: 2250-284X , E ISSN : 2250-2858
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