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Adult Granulosa Cell Tumor with amyloid like stroma of Ovary

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Abstract (2. Language): 
Granulosa cell tumor accounts for 1.5% of all ovarian neoplasms. It is an estrogen producing neoplasm. It is of two types, an adult type that occurs mainly in postmenopausal women and a juvenile type that usually occurs in prepubertal girls and women younger than 30 years. The common presenting symptoms are abnormal vaginal bleeding in postmenopausal woman and menorrhagia, metrorrhagia or amenorrhea in those who are premenopausal. Complete surgical resection of the tumor is the treatment of choice. Recurrent disease tends to occur many years after the initial diagnosis so long-term follow up is needed. We report a case of adult granulosa cell tumor in a 55 year old woman.
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REFERENCES

References: 

1. Stage AH, Grafton WD. Thecomas and granulosa-theca cell tumors of the ovary. An analysis of 51 tumors.
Obstet Gynecol 1977; 50: 21-7.
2. Savage P, Constenla D, Fisher C, Shepherd JH, Barton DP, Blake P, Gore ME. Granulosa cell tumors of
the ovary: Demographics, survival and the management of advanced disease. Clinical Oncology 1998;10:
242-5.
3. Rokitansky CV. Über Abnormalitäten des Corpus Luteum. Wien Med Ztc 1859;4: 253-4.
4. Scully RE. Juvenile granulosa cell tumor. Pediatr Pathol 1988;8:423-7.
Indian Journal of Basic & Applied Medical Research; September 2013: Issue-8, Vol.-2, P. 1047-1051
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5. Rossing MA, Daling JR, Weiss NS, Moore DE, Self SG. Ovarian tumors in a cohort of infertile women. N
Engl J Med 1994; 331: 771-6.
6. Aboud E. A review of granulosa cell tumors and thecomas of the ovary. Arch Gynecol Obstet 1997; 259 :
161-5.
7. Nakashima N, Young RH, Scully RE. Androgenic granulosa cell tumors of the ovary. A clinicopathologic
analysis of 17 cases and review of the literature. Arch Pathol Lab Med. 1984; 108 : 786 – 91.
8. Morikawa K, Hatabu H, Togashi K, Kataoka ML, Mori T, Konishi J. Granulosa cell tumor of the ovary:
MR findings. J Comput Assist Tomogr 1997; 21: 1001-4.
9. Norris HJ, Taylor HB. Prognosis of granulosa-theca tumors of the ovary. Cancer 1968; 21: 255-63.
10. Choi YL, Kim HS, Ahn G. Immunoexpression of inhibin alpha subunit, inhibin/activin betaA subunit and
CD99 in ovarian tumors. Arch Pathol Lab Med 2000;124: 563-9.
11. McCluggage WG, Maxwell P. Immunohistochemical staining for calretinin is useful in the diagnosis of
ovarian sex cord-stromal tumors. Histopathology 2001;38: 403-8.
12. Pectasides D, Pectasides E, Psyrri A. Granulosa cell tumor of the ovary. Cancer Treatment Reviews 2008;
34(1): 1–12.
13. East N, Alobaid A, Goffin F, Ouallouche K, Gauthier P. Granulosa cell tumor: a recurrence 40 years after
initial diagnosis. Journal of Obstetrics and Gynaecology Canada 2005; 27( 4): 363–4.
14. Colombo N, Parma G, Zanagnolo V, Insinga A. Management of ovarian stromal cell tumors. Journal of
Clinical Oncology 2007; 25(20) : 2944–51.
15. McNeilage J, Alexiadis M, Susil BJ, Mamers P, Jobling T, Laslett G, et al. Molecular characterization of
sarcomatous change in a granulosa cell tumor. International Journal of Gynecological Cancer 2007;17(2):
398–406.
16. Miller BE, Barron BA, Dockter ME, Delmore JE, Silva EG, Gershenson DM. Parameters of differentiation
and proliferation in adult granulosa cell tumors of the ovary. Cancer Detect Prev 2001; 25: 48-54.
17. Koukourakis GV, Kouloulias VE, Koukourakis MJ, Zacharias GA, Papadimitriou C, Mystakidou K, et al.
Granulosa cell tumor of the ovary: tumor review. Integr Cancer Ther 2008;7:204-15.

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