Buradasınız

Anasayfa » Content

The Evaluation of Serum Fasting Blood Sugar and Lipid Profile including Apo A and Apo B in Diabetic Retinopathy Subjects

The Evaluation of Serum Fasting Blood Sugar and Lipid Profile including Apo A and Apo B in Diabetic Retinopathy Subjects

Journal Name:

  • Indian Journal of Basic & Applied Medical Research

Publication Year:

  • 2012

Key Words:

Author Name
Abstract (2. Language): 
Background: Blindness is one of major complications of type 2 DM. The aim of this study was to evaluate the lipid profile including Apo A and Apo B levels in diabetes with and without retinopathy patients of South Indian rural population and then to correlate them. Materials & Methods:The present study was done at PES Institute of Medical Sciences and Research, Kuppam involving in-patients and out-patients attending PESIMSR hospital. The total numbers of subjects were 90 divided into three groups. Group I- 30 healthy controls, Group II - 30 diabetes without retinopathy and Group III - 30 were diabetic retinopathy in age group between 45-75years. The investigations carried out were FBS, TC, TG, HDL-cholesterol and apolipoproteins A & B. Results:There were increased FBS, TC, TG and Apo B levels in diabetics with and without retinopathy. Decreased levels of HDL in Group II & III were observed. Triglyceride level and Apo B levels was found to be increasing with the severity of retinopathy. Positive correlation of Apo A with HDL among diabetics with and without retinopathy. Conclusion: Rigorous lipid control needs to be followed as it is known for health benefits, so as to prevent cardiovascular disease and ocular morbidity, thereby increasing the quality of life and vision among diabetics
Bookmark/Search this post with
FULL TEXT (PDF): 
PDF icon arastirmax-evaluation-serum-fasting-blood-sugar-and-lipid-profile-including-apo-and-apo-b-diabetic-retinopathy-subjects.pdf
  • 2
94-102
  • English

REFERENCES

References: 

1. Tien Yin Wong, Bonald Klew, Amirul
Islam, Mary Frances Cotch, Aaron R.
Folsom, Barbara E.K. Klein, A. Richey
Sharrett, and Steven Shea, for the
(MESA)., Diabetic Retinopathy a multiethnic
cohort in the united states.
American journal of ophthalmology.
2006;141:446-455.
2. D.H.Wsu Kt yea. Diabetic retinopathy
and serum lipids. Singapore Medj 2000;
41(6): 295-297.
3. T. A. Chowdhuory, D Hopkinal, P.M.
Dodson, GC Vafidis. The role of serum
lipids; n exudative diabetic maculopathy
: is there a place for lipid lowering
therapy. Eye. 2002; 16:689-693.
4. Gupta sunil, Ambade. Ajays;
prevalence of Diabetic retinopathy and
Influencing factors amongst type 2
Diabetics from central India. 2004; 24:
75-78(Issue3).
5. Emily Y.Chew, MD; Michael L.Klein,
MD, Frederick, Ferris III, Nanly, A.
Remalees, MS, Robert P. Murphy,
Kathoryn chantry, Byronz, Hooqwef,
Dayton miller. Association of elevated
serum lipid levels with retinal Hard
exudates in diabetic retinopathy.
Archopthalmal. 1996;114:1079-1084.
6. M. Rema, B.K. Srivastava, B. Arhma,
R. Deena, V. Mohan. Association of
serum lipids with diabetic retinopathy
in urban South Indians- the Chennai
urban Rural Epidemiology study
(CURES) Eye study – 2;
Diabet: Med. 2006; 23: 1029-1036.
7. A.H. Kissebah, E.M. Kohner, B.
Lewis, Y.K. siddio, C.Lowy. Plasma-
Lipids and glucose/insulin relationship
in Non-insulin Requiring. Diabetics
with and without retinopathy;
The Lancet. May1995; 17: 1104 –
1106.
8. Carl A, Burtis, Edward R. ashwood,
Tietz Text book of clinical chemistry
3rd edition.1999 by the W.B Sunders
Company, 829-868.
9. GofmantW, Lidrigren F.T, Ellito H.
Bio. Chem.1949,179:973.
10. Ray Sahelian M.D, H, Ned Rood.
Diabetic Retinopathy .2005, Spring: 8
(1): 1-7.
Indian Journal of Basic & Applied Medical Research; March 2012: Issue-2, Vol.-1, P. 94-102
102
www.ijbamr.com
11. Biljana Milsanovic; Roberts J. glynn, David M.
Nathan JoAnn E. Manson and Debra A,
Schanmberg. A prospective study of serum
lipids and risk of diabetic macular edema in
type 1 diabetic. Diabetic. 2004;53:2883-2892.
12. Dlirsp. Daliya. Rajuir, Ram Jagat, Dash RJ,
Chakravatutinro. serum lipoprotein cholesterol
profile in diabetic retinopathy. Indian
J.opthalmol. 1984,32: 89-91.
13. Bruce Gordon, Stanley Chang, Mary
Kavanagh, Maria. Berrocal, Lawrence
Yannuzzi, Caralyn Robertyon & and Rew
Drexler.The effects of lipid lowering on
Diabetic Retinopathy. American Journal of
ophthalmology. 1991; 122:385-391.
14. Timothy.J.Lyons, Alicia J. Jenkins, Deyi
Zheng, Daniet J. Lacklond, Daniel MC, Gee,
W. Timothy Garvees, Richarel L. Klein. The
DCCT, EDIC. Diabetic retinopathy and serum
lipoprotein subclasses in the DCCT/EDK
Chart. Invert opthal via. 2004; 45:910-918.
15. Hendrika. VanLeiden, Jacqueline, M Dekkert,
Annette C. Moll, Giel Nijpels, Robert J. Heine,
Lex M. Bouter, Coen D.A. Stehouwer, Bettine.
Blood Pressure, Lipids and obesity are
associated with retinopathy. The Hoorn study
Diabetic care.2002;25:1320-1325.
16. Ishrat Kareem, SA. Jaweed, J.S. Bardapurkar,
V.P. Patil; Study of magnesium, glycosylated
hemoglobin and lipid profile in diabetic
retinopathy; Indian Journal of clinical
Biochemistry. 2004; 19(2): 124-127.
17. Lyons Timthy J. Jenkins Alicia. S.
Deyizheng, Lackland Daniet T.
Mcgee Daniel. Diabetic Retinopathy
and serum lipoprotein subclasses in
the DCCT/EDIC cohort:
Investigative opthalogy & visual
science.2004; 25:910-918.
18. Barbara E.K. Klein, Ronald Klein,
and scot E.Moss. Is serum cholesterol
Associated with progression of
Diabetic Retinopathy or Macular
Edema in persons with younger onset
Diabetes of Long duration. American
Journal of
ophthalmology.1999;128:652-654.

Thank you for copying data from http://www.arastirmax.com