Buradasınız

Anasayfa » Content

Bifosfonat Kullanımına Bağlı Maksillada Osteonekroz: Olgu Sunumu

Maxillary Osteonecrosis Related to Bisphosphonate Use: A Case Report

Journal Name:

  • Fırat Tıp Dergisi

Publication Year:

  • 2011

Key Words:

Keywords (Original Language):

Author NameUniversity of AuthorFaculty of Author
Abstract (2. Language): 
Bisphosphonates are widely used in the treatment of hypercalcemia associated with breast, prostate or lung cancer and the metastatic osteolytic lesions of multiple myeloma. One of the most significant side effects of bisphosphonates is the occurrence of osteonecrosis of the maxilla and the mandible. In this case report, we presented a 64 year-old male patient who was receiving bisphosphonates for bone metastasis of prostate cancer with a history of approximately six months ago left upper second molar extraction and a physical examination finding of oroantral fistula.
Bookmark/Search this post with
Abstract (Original Language): 
Bifosfonatlar meme, prostat ve akciğer kanserlerine bağlı gelişen hiperkalseminin ve multipl myelomaya bağlı metastatik osteolitik lezyonların tedavisinde yaygın olarak kullanılmaktadır. Bifosfonatların en önemli yan etkilerinden biri mandibula ve maksillada yaptığı osteonekrozdur. Bu makalede, yaklaşık 6 ay önce sol üst 2. molar diş çektirme öyküsü olan, muayenesinde oroantral fistül tespit edilen ve kemik metastazı yapmış prostat kanseri nedeniyle bifosfonat kullanan 64 yaşında erkek hasta sunuldu.
FULL TEXT (PDF): 
PDF icon arastirmax-bifosfonat-kullanimina-bagli-maksillada-osteonekroz-olgu-sunumu.pdf
  • 3
160-163
  • Turkish

REFERENCES

References: 

1. Van Poznak C, Estilo C. Osteonecrosis of the jaw in cancer patients receiving IV bisphosphonates. Oncology 2006; 20: 1053-1062.
2. Alıcı S, Çekici S. Malign hastalıklarda bisfosfonatların rolü. Van Tıp Dergisi 2002; 9: 66-72.
3. Duman AE, Güven GS, Gürlek A. Erkek osteoporozu. Hacet¬tepe Tıp Dergisi 2005; 36: 175-183.
4. Benhamou CL. Effects of osteoporosis medications on bone
quality. Joint Bone Spine 2007; 74: 39-47.
162
Fırat Tıp Dergisi 2011;16(3): 160-163
5. Woo SK, Hellstein JW, Kalmar JR. Systematic review: Bisphosphonates and osteonecrosis of the jaws. Ann Inter Med 2006; 144: 753-61.
6. Akarslan Z, Kahraman S. Kemik
metastaz
ı yapmış prostat kanser tedavisinde kullanılan bifosfonata bağlı olarak çene kemiklerinde gelişen osteonekroz : vaka raporu ve literatür derlemesi. Atatürk Üniv Diş Hek Fak Derg 2008; 3: 105-110.
7. Marx RE, Cillo JE, Ulloa JJ. Oral bisphosphonate-induced osteonecrosis: risk factors, prediction of risk using serum CTX testing, prevention, and treatment. J Oral Maxillofac Surg
2007; 65: 2397-410.
8. Reid IR, Bolland MJ, Grey AB. Is bisphosphonateassociated osteonecrosis of the jaw caused by soft tissue toxicity? Bone 2007; 41: 318-20.
9. Landesberg R, Cozin M, Cremers S et al. Inhibition of Oral Mucosal Cell Wound Healing by Bisphosphonates. J Oral
Maxillofac Surg 2008; 66: 839-47.
10. Naidu A, Dechow PC, Spears R et al. The effects od bisphosphonates on osteoblasts in vitro. Oral Surg Oral Med
Oral Pathol Oral Radiol Endod 2008; 106: 5-13.
11. Montebugnoli L, Felicetti L, Gissi BD et al. Biphosphonate-associated osteonecrosis can be controlled by nonsurgical management. Oral Surg Oral Med Oral Pathol Oral Radiol
Endod 2007; 104: 473-477.
Özer ve Bayar
12. Lehrer S, Montazem A, Ramanathan L et al. Bisphosphonate-Induced Osteonecrosis of the Jaws, Bone markers, and a Hypothesized Candidate Gene. J Oral Maxillofac Surg 2009; 67: 159-161.
13. Leite AF, Figueiredo PT, Melo NS et al. Bisphosphonate associated osteonecrosis of the jaws. Report of a case and literature review. Oral Surg Oral Med Oral Pathol Oral Radiol
Endod 2006; 102: 14-21.
14. Gutta R, Louis PJ. Bisphosphonates and osteonecrosis of the jaws: Science and rationale. Oral Surg Oral Med Oral Pathol
Oral Radiol Endod 2007; 104: 186-193.
15. Song K, Min Y, Lee J et al. A Probable Case of Oral Bisphosphonate-Associated Osteonecrosis of the Jaw and recovery with Parathyroid Hormone Treatment. Current
Therapeutic Research 2008; 69: 356-362.

Thank you for copying data from http://www.arastirmax.com