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HYDROGEL AS A PROMISING DRUG DELIVERY SYSTEM: AN OVERVIEW

Journal Name:

  • Advance Research in Pharmaceuticals and Biologicals

Publication Year:

  • 2012

Key Words:

Author Name
Abstract (2. Language): 
Hydrogels are three dimensional hydrophilic polymer networks capable of swelling in water or biological fluids. Their ability to absorb water is due to the presence of hydrophilic groups. Hydrogels play a critical role in many tissue engineering scaffolds, biosensor and bioMEMS devices and drug carries. Hydrogels have attracted considerable attention as excellent candidates for controlled release devices. Hydrogels can also be engineered to exhibit bio-adhesiveness to facilitate drug targeting, especially through mucus membranes, for non-invasive drug administration. Hydrogel based drug delivery devices have become a major area of research interest with several commercial products already developed. With ongoing research in advanced drug delivery formulations to provide stable and economical drug delivery systems, the focus is on hydrogel which are known to reduce the problems of not only conventional dosage forms but also of novel drug delivery systems which require a biocompatible, convenient and stable drug delivery system for molecules as small as NSAIDs (Non-steroidal anti-inflammatory drugs) or as large as proteins and peptides. In present review article, our aim is to highlight the promising benefits offered by hydrogel delivery system in delivery of many drug moieties.
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  • 4
310-315
  • English

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