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Pneumocystis Jiroveci Enfeksiyonu ve Akciğer Tutulumu

Pneumocystis jiroveci Infection and Lung Involvement

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Abstract (2. Language): 
Pneumocystis jiroveci is an oppurtunistic pathogen especially affecting lungs in immune-suppressed patients. The clinical findings in Pneumocystis jiroveci pneumonia are dyspnea, tachypnea, nonproductive cough, fever and cyanosis. Interstitial pneumonia is demonstrated radiologically. As it can not be cultured, the diagnosis is made with the presence of clinical findings and the morphological demonstration of the organism in the secreation of lung or detection with more sensitive methods like fluorescence antibody and molecular methods. Although other drug alternatives exist, trimethoprime-sulphamethaxasole is offered as the first option in the prophylaxis and treatment.
Abstract (Original Language): 
Pneumocystis jiroveci, bağışıklık sistemi baskılanmış hastalarda özellikle akciğer tutulumu ile seyreden fırsatçı bir patojendir. Pneumocystis jiroveci pnömonisinde klinik bulgular dispne, taşipne, nonprodüktif öksürük, ateş ve siyanozdur. Radyolojik olarak interstisyel pnömoni görünümü saptanır. Kültürde üretilemediğinden tanı klinik bulgular ile birlikte akciğer sekresyonunda organizmanın morfolojik olarak gösterilmesi veya fluoresan antikor ve moleküler yöntemler gibi daha duyarlı yöntemler ile saptanması ile konulabilmektedir. Diğer ilaç alternatifleri bulunmakla birlikte trimetoprim-sulfametaksazol profilaksi ve tedavide ilk seçenek olarak önerilmektedir.
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