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Ailevi Akdeniz Ateşi ile İzlenen bir Hastada IgA Nefriti: 5 Yıllık Takip

IgA Nephritis in a Patient with Familial Mediterranean Fever: 5 Years-Follow-up

Journal Name:

  • Türk Nefroloji, Diyaliz ve Transplantasyon Dergisi

Publication Year:

  • 2010
DOI: 
DOI 10.5262/tndt.2010.1003.15

Key Words:

Keywords (Original Language):

Author NameUniversity of AuthorFaculty of Author
Abstract (2. Language): 
Familial Mediterranean Fever (FMF) is an inflammatory autosomal recessive disease characterized by serosal and synovial involvement. Although secondary amyloidosis is the most common of the renal diseases observed with FMF, other glomerular involvements have also been demonstrated. Unfortunately only a few cases about IgA nephritis in patients with FMF have been reported in literature. Here we present a 56-year-old male patient who was diagnosed with chronic IgA nephritis by renal biopsy after detection of intermittent hematuria and proteinuria while he was being monitored for FMF disease. The patient was followed up for 5 years and treated with regular colchicine. Our case shows that amyloidosis is not only the type of renal involvement in patients with FMF. Kidney biopsy should be performed in patients with FMF displaying micro- or macroscopic hematuria with or without proteinuria.
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Abstract (Original Language): 
Ailevi Akdeniz Ateşi (AAA) serozal ve synovial tutulumla karakterize inflamatuvar otozomal resesif bir hastalıktır. AAA ile birlikte en sık görülen böbrek tutulumu sekonder amiloidoz olmasına rağmen nadiren diğer glomerüler hastalıklarla da birliktelik tanımlanmıştır. Maalesef literatürde AAA ile IgA Nefriti nadiren bir arada tanımlanmıştır. Biz burada AAA tanısı ile izlenirken tekrarlayan hematüri ve proteinüri tespit edildikten sonra renal biyopsi yoluyla Kronik IgA Nefriti tanısı konulan 56 yaşındaki erkek hastayı sunduk. Hasta beş yıldır polikliniğimizde takip ediliyor ve düzenli kolşisin tablet kullanıyordu. Olgumuz AAA’lı hastalarda böbrek tutulumunun tek tipinin amiloidoz olmadığını göstermektedir. Proteinüri olsun ya da olmasın mikroskopik veya makroskopik hematüri tespit edilen tüm AAA’lı hastalarda böbrek biyopsisi yapılmalıdır.
FULL TEXT (PDF): 
PDF icon arastrmx_172977_19_pp_224-227.pdf
  • 3
224-227
  • Turkish

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5 Years-Follow-up
Türk N efroloji D iyaliz ve Transplantasyon D ergisi
Turkish Nephrology, Dialysis and Transplantation Journal
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