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Aksiller brakial pleksus bloğunda iki ajanla karşılaştırmalı çalışma: Bupivakain ve Levobupivakain

Comparative study of two agents in axillary brachial plexus block: Bupivacaine vs Levobupivacaine

Journal Name:

  • Smyrna Tıp Dergisi

Publication Year:

  • 2011

Key Words:

Keywords (Original Language):

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Abstract (2. Language): 
Objective: The prospective, randomized study aimed to investigate whether there is significant difference between the block and analgesic quality variables of morphine adjuncted bupivacaine and levobupivacaine in axillary perivascular brachial plexus. Material and Methods: Thirty five ASA physical status I-II patients, aged 18-70 years scheduled for upper limb surgery under axillary brachial plexus anaesthesia were randomly allocated into two groups. Group B (n:20): 40 mL 0.375% bupivacaine + 2 mg morphine and Group L (n:15): 40 mL 0.375% levobupivacaine + 2 mg morphine. Sensorial block onset time, motor block onset time, duration of sensorial block and first analgesic requirement time were recorded in each of the groups. Results: Significant difference between axillary levobupivacaine and bupivacaine performed groups respect to sensorial block onset time (Group B: 13.40±2.76 minutes, Group L: 9.66±2.52 minutes, p<0.0001), motor block onset time (Group B: 9.20±1.73 minutes, Group L: 6.40±2.55 minutes, p<0.0001) and duration of sensorial block (Group B: 1167.15±48.14 minutes, Group L: 1057.33±48.14 minutes, p<0.0001) were found. Conclusion: We think that levobupivacaine may be preferred for its rapid sensorial and motor onset time
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Abstract (Original Language): 
Amaç: Bu prospektif randomize çalışmada; aksiler perivasküler brakial pleksusda, morfin destekli bupivakain ve levobupivakainin blok ve analjezik kalite açısından belirgin farklılık gösterip göstermediğinin araştırılması amaçlanmıştır. Gereç ve Yöntem: Brakial pleksus anestezisi altında üst ekstremite cerrahisi planlanan, 18-70 yaş arası, ASA fiziksel durumu I-II olan 35 hasta rastgele iki gruba ayrıldı. Grup B (n:20): 40 mL %0,375 bupivakain + 2 mg morfin ve grup L (n:15): 40 mL %0,375 levobupivakain + 2 mg morfin. Duyusal blok başlangıç zamanı, motor blok başlangıç zamanı, duyusal blok süresi ve ilk analjezik gereksinim süresi grupların her birinde kaydedildi. Bulgular: Uygulanan gruplarda, aksiler levobupivakain ve bupivakain arasında duyusal blok başlangıç zamanı açısından (Grup B: 13,40±2,76 dakika, Grup L: 9,66±2,52 dakika, p<0.0001), motor blok başlangıç zamanı açısından (Grup B: 9,20±1,73 dakika, Grup L: 6,40±2,55 dakika, p<0.0001), ve duyusal blok süresi açısından (Grup B: 1167,15±48,14 dakika, Group L: 1057,33±48,14 dakika, p<0.0001) anlamlı ilişki tespit edildi. Sonuç: Hızlı duyusal ve motor başlangıç zamanlarından dolayı, levobupivakainin tercih edilebileceğini düşünmekteyiz.
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  • 1
27-34
  • Turkish

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Correspondence:
Dr. Sinem Sarı AK
Adnan Mendres Üniversitesi
Anesteziyoloji ve Reanimasyon AD Aydın, Turkiye
tel: +90.256.4441256 /2115
mail: sarisinem@yahoo.com

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