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Orta Yaş Hipertansif Bireylerde Kan Basıncı Kontrolü ve Uyku Kalitesi Arasındaki İlişkinin Analizi

An Analysis of The Relation Between Blood Pressure Regulatıon and Sleep Quality in Middle Aged Hypertensıve Subjects

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Abstract (2. Language): 
In the present study, we aimed to evaluate the effect of blood pressure regulation on sleep quality in the hypertensive subjects and determine blood pressure parameters related with poor sleep quality. Our study is a cross-sectional study including 90 hypertensive subjects at age between 35 and 65 years. The patients were performed 24-hour ambulatory blood pressure monitoring and divided into those with regulated blood pressure group and poor blood pressure control group. Sleep quality was checked before the ambulatory blood pressure monitoring by using Pittsburgh sleep quality test. Statistical analyses were performed with SPSS 13.0 packet program. Global Pittsburgh sleep quality index (PSQI) scoring were similar in both groups and when components of the sleep quality were evaluated, daytime dysfunction was significantly higher in patients with poor blood pressure control compared to patienst with regulated blood pressure (1.0±0.9 versus 1.4±1.0, p=0.05; respectively ). Global PSQI score did not show significant correlation with arterial blood pressure leveles, pulse pressure, and systolic blood pressure levels. However, night diastolic pressure levels were weakly correlated with global PSQI scoring (r=0.16, p=0.04). Only diastolic non-dipper status was found as independent predictor of poor sleep quality as a result of logistic regression analysis (Odds: 3.21 (CI: 1.51-7.72), p=0.03). In the present study, sleep quality was markedly impaired in hypertensive patients and diastolic non-dipper was determined as an independent predictor of poor sleep quality. It seems important to assess sleep quality in patient with diastolic non-dipper at ambulatuary blood pressure evaluation, especially for detection of poor sleep status.
Abstract (Original Language): 
Bu çalışmada orta yaş hipertansif hastalarda kan basıncı regülasyonun uyku kalitesi üzerine etkisini ve kötü uyku kalitesi ile ilişkili kan basıncı parametrelerin neler olduğunu belirlemeyi amaçladık Çalışmamız yaşları 35 ile 65 arasında değişen 90 hipertansif hastanın alındığı kesitsel bir çelışmadır. Hastalara 24 saatlik ambulatuvar kan basıncı holteri takılarak kan basıncı ortalamalarına göre hastalar regüle KB olanlar ve kötü KB kontrolü olanlar olarak iki gruba ayrılmıştır. Uyku kalitesi ambulatuvar kan basıncı holteri takılmadan önce Pittsburgh uyku kalitesi testi ile değerlendirildi. İstatistiksel analiz için SPSS 13.0 paket programı kullanıldı. Global Pittsburgh uyku kalite indeksi(PSQI) skoru her iki grupta benzerdi ve uyku kalitesinin bileşenleri incelendiğinde yalnız gündüz işlev bozukluğu kötü kan basıncı kontrolü grubunda anlamlı olarak artmıştı (1,0±0,9 ve 1,4±1,0 p=0.05 ). Global PSQI skoru ile ortalama arteriyal kan basıncı, nabız basıncı, sistolik kan basıncı arasında korelasyon tespit edilmedi, gece diyastolik KB ile zayıf korelasyon mevcuttu(r=0.16 p=0.04). Kötü uyku kalitesinin öngördürücülerini tespit etmek için yapılan lojistik regresyon analizinde yalnızca diyastolik non-dipper durumunun bozulmuş uyku kalitesi açısından bağımsız öngördürücü olduğu tespit edildi(odds 3,21(CI: 1,51-7,72) p=0.03) Çalışmamızda hipertansif hastalarda uyku kalitesinin belirgin şekilde bozulduğu, diyastolik non-dipper’in bozulmuş uyku kalitesi açısından bağımsız öngördürücü olduğu tespit edilmiştir. Ambulatuvar KB ölçümlerinde diyastolik non-dipper tespit edilen hastalarda uyku kalitesinin sorgulanması, bu hastalarda uyku bozukluğunu tespiti açısından önemli görünmektedir
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