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NORMAL KORONER ANJİOGRAFİSİ BULUNAN HASTALARDA MİYOKARD PERFÜZYON SPECT’TE İZLENEN DEFEKT LOKALİZASYONLARI İLE KORONER ARTER HASTALIĞI İÇİN RİSK FAKTÖRLERİ ARASINDAKİ İLİŞKİ

THE RELATIONSHIP BETWEEN THE LOCALIZATION OF MYOCARDIAL PERFUSION DEFECTS AND RISK FACTORS FOR CORONARYARTERY DISEASE IN PATIENTS WITH NORMAL CORONARYANGIOGRAPHY

Journal Name:

  • İstanbul Tıp Fakültesi Dergisi

Publication Year:

  • 2005

Key Words:

Keywords (Original Language):

Author NameUniversity of AuthorFaculty of Author
Abstract (2. Language): 
Objective: The aim of this study was to investigate the relationship between the risk factors for systemic vascular diseases and the localization of the perfusion defects in patients having ischemic perfusion defects in myocardial SPECT with normal coronal angiography. Materials and methods: In this retrospective study, a total of 69 (47 female, 22 male, mean age 53±10 years) patients with ischemic perfusion defect in myocardial SPECT with normal coronal angiography in three months after the myocardial SPECT were enrolled. Of these patients; 55 (80%) and 14 (20%) had treadmill exercise and pharmacological stress tests, respectively. Imaging of these patients was performed with single day stress and rest protocol. Fisher’s exact test and Chi-square tests were used for statistical analysis. Results: Risk factors for systemic vascular diseases were as follows: hypertension in 44, hyperlipidemia in 32, diabetes in 12 patients. Effort test was found to be positive in 19 (29.7%) of the patients. Gender was significantly associated with occlusion of the right coronary artery, while hypertension was significantly associated with the occlusion of the circumflex artery. Among predictive risk factors, patients with hypertension had more lateral wall perfusion defects compared with the patients with other risk factors. In addition, anterior perfusion defects were more encountered in female patients, while inferior perfusion defects were more detected in male patients. Conclusion: Breast attenuation in women and diaphragm attenuation in men and lateral wall perfusion defects in hypertensive patients with normal coronary angiography having myocardial perfusion defects may lead to false positive interpretations
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Abstract (Original Language): 
Amaç: Bu çal›flman›n amac›, miyokard perfüzyon SPECT’te iskemik perfüzyon defekti olan, koroner anjiografisi normal bulunan kiflilerde, koroner arter hastal›¤› için prediktif risk faktörlerinin da¤›l›m› ve risk faktörleri ile perfüzyon defektlerinin lokalizasyonlar› aras›ndaki iliflkinin araflt›r›lmas›d›r. Gereç ve yöntem: Miyokard perfüzyon SPECT’te iskemi düflündüren perfüzyon defekti olan ve sintigrafiden sonra en fazla üç ay içerisinde yap›lan koroner anjiografileri normal bulunan toplam 69 hasta (47 kad›n, 22 erkek; ortalama yafl: 53±10 y›l) retrospektif olarak incelendi. Ellibefl (%80) hastaya yürüme band›nda egzersiz, 14 (%20) hastaya farmakolojik stres testi yap›ld›. Görüntülemede tek gün stres/rest protokolü uyguland›. Çal›flmada istatistik yöntemi olarak Fisher’s exact test ve ki-kare testleri kullan›ld›. Bulgular: Hastalar›n 44’ünde hipertansiyon, 32’sinde hiperlipidemi, 12’sinde diabet öyküsü vard›. Efor testi hastalar› n 19’unda (%27,5) pozitif olarak bulundu. Cinsiyet ile koroner arterlerden sa¤ koroner arter (RCA), hipertansiyon ile ise sirkumfleks (Cx) alan› aras›ndaki iliflki istatistiksel olarak anlaml› bulundu (p<0,05). Kad›nlarda anterior ve erkeklerde inferior duvarda perfüzyon defektlerinin daha s›k görüldü¤ü izlendi. Sonuç: Koroner anjiografileri normal bulunan kad›n hastalarda meme, erkek hastalarda diafragma attenüasyonu ve hipertansiyonu bulunan hastalarda lateral duvar perfüzyon defektleri yanl›fl pozitif sonuçlara neden olabilmektedir.
FULL TEXT (PDF): 
PDF icon arastirmax-normal-koroner-anjiografisi-bulunan-hastalarda-miyokard-perfuzyon-spectte-izlenen-defekt-lokalizasyonlari-ile-koroner-arter-hastaligi-icin-risk-faktorleri-arasindaki.pdf
  • 4
97-101
  • Turkish

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