You are here

Sol atriyal miksomalar ve cerrahi tedavisi

Left atrial myxomas and surgical treatment

Journal Name:

Publication Year:

Keywords (Original Language):

Author Name
Abstract (2. Language): 
This report summarizes our ten-year experience with atrial myxomas. Of the 17 patients who underwent resection of left atrial myxoma between January 2000 and December 2009, 11 were females and 6 males, and their mean age was 53.47±17.4 years. There was history of a cerebral emboli in 2 patients. All myxomas were located in the left atrium. For tumor resection left atriotomy was used in 16 patients, while transseptal approach was used in one patient with foramen ovale. No early or late mortality was observed. The patients were followed regularly with annual echocardiography in the follow up period. No recurrence was noted in the follow up period. Immediate surgical treatment should be performed after the diagnosis to prevent the risk of embolization and sudden cardiac death. Periodic controls with annual echocardiographic examinations are mandatory since early or late recurrence is possible in these tumors.
Abstract (Original Language): 
Bu yazıda atriyal miksomalardaki on yıllık deneyimimiz sunulmuştur. Ocak 2000 ile Aralık 2009 arasında sol atriyal miksoma tanısı ile cerrahi tedavi uygulanan 17 hastanın 11’i kadın, 6’sı erkekti ve ortalama yaşı 53.47±17.4 yıl idi. İki hastada serebral emboli öyküsü mevcuttu. Tüm hastalarda miksoma sol atriyum yerleşimliydi. Miksoma rezeksiyonu için 16 hastada sol atriyotomi, patent foramen ovalesi olan bir hastada ise transseptal yaklaşım kullanıldı. On dört hastada sadece endotelyal düzeyde tümör rezeksiyonu uygulandı. Erken ve geç dönemde mortalite gelişmedi. Hastalar takip periyodunda 1 yıllık aralıklarla ekokardiyografi ile düzenli olarak takip edildiler. Hiçbir hastada takip periyodunda nüks gözlenmedi. Tanı konulduktan sonra embolizasyon ve ani kardiyak ölüm riskini ortadan kaldırmak için en kısa süre içerisinde cerrahi tedavi yapılmalıdır. Bu tümörlerde erken ve geç dö- nemde nüks görülebileceği için, yıllık ekokardiyografik kontrollerle periyodik takip yapılması gerekmektedir.
38-42

REFERENCES

References: 

1. Binning MJ, Sarfati MR, Couldwell WT. Embolic atrial
myxoma causing aortic and carotid occlusion. Surg
Neurol 2009; 71: 246-249.
2. Gonzalez-Juanatey C, Regueiro-Abel M, Lopez-Agreda
H, Peña-Martínez F, Gonzalez-Gay MA. Giant left atrial
myxoma mimicking severe mitral valve stenosis Int J
Cardiol 2008; 127: e110-112.
3. Reynen K. Cardiac myxomas. N Engl J Med 1995; 333:
1610-1617.
4. Panos A, Kalangos A, Sztajzel J. Left atrial myxoma
presenting with myocardial infarction. Case report and
review of the literature. Int J Cardiol 1997; 62: 73-75.42 • Mart 2011 • Gülhane Tıp Derg Şahin ve ark.
5. Vogt PR, Jenni R, Turina MI. Infected left atrial myxoma
with concomitant mitral valve endocarditis. Eur J
Cardiothorac Surg 1996; 10: 71-73.
6. Riad MG, Parks JD, Murphy PB, Thangathurai D.
Infected atrial myxoma presenting with septic shock. J
Cardiothorac Vasc Anest 2005; 19: 508-511.
7. Keeling IM, Oberwalder P, Anelli-Monti M, et al. Cardiac
myxomas: 24 years of experience in 49 patients. Eur J
Cardiothorac Surg 2002; 22: 971-977.
8. Bhan A, Mehrotra R, Choudhary SK, et al. Surgical
experience with intracardiac myxomas: long-term
follow-up. Ann Thorac Surg 1998; 66: 810-813.
9. Fang BR, Chiang CW, Hung JS, Lee YS, Chang CS.
Cardiac myxoma-clinical experience in 24 patients. Int
J Cardiol 1990; 29: 335-341.
10. Meyns B, Vancleemput J, Flameng W, Daenen W.
Surgery for cardiac myxoma. A 20-year experience with
long-term follow-up. Eur J Cardiothorac Surg 1993; 7:
437-440.
11. McAllister HA. Primary tumors of the heart and
pericardium. Curr Probl Cardiol 1979; 4: 1-51.
12. Goswami KC, Shrivastava S, Bahl VK, Saxena A,
Manchanda SC, Wasir HS. Cardiac myxomas: Clinical
and echocardiographic profile. Int J Cardiol 1998; 63:
251-259.
13. Acikel M, Yekeler I, Ates A, Erkut B. A giant left atrial
myxoma: an unusual cause of syncope and cerebral
emboli. Int J Cardiol 2004; 94: 325-326.
14. Shavit L, Appelbaum L, Grenader T. Atrial myxoma
presenting with total occlusion of the abdominal aorta
and multiple peripheral embolism. Eur J Int Med 2007;
18: 74-75.
15. Ha JW, Kang WC, Chung N, et al. Echocardiographic
and morphologic characteristics of left atrial myxoma
and their relation to systemic embolism. Am J Cardiol
1999; 83: 1579-1582.
16. Obeid AI, Marvasti M, Parker F, Rosenberg J. Comparison
of transthoracic and transesophageal echocardiography
in diagnosis of left atrial myxoma. Am J Cardiol 1989;
63: 1006-1008.
17. Ridge CA, Killeen RP, Sheehan KM, et al. Giant right
atrial myxoma: characterization with cardiac magnetic
resonance imaging. Clin Imag 2010; 34: 231-233.
18. Bhan A, Mehrotra R, Choudhary SK, et al. Surgical
experience with intracardiac myxomas: long-term
follow-up. Ann Thorac Surg 1998; 66: 810-813.
19. Jones DR, Warden HE, Murray GF, et al. Biatrial approach
to cardiac myxomas: A 30-year clinical experience. Ann
Thorac Surg 1995; 59: 851-856.
20. Kabbani SS, Jokhadar M, Meada R, et al. Atrial myxoma:
Report of 24 operations using the biatrial approach.
Ann Thorac Surg 1994; 58: 483-488.
21. Zeebregts C, Schepens M, Knaepen PJ. Extended vertical
transatrial septal approach for the removal of left atrial
myxoma. Eur J Cardiothorac Surg 1998; 13: 90-93.
22. Luisi VS, Caparrotti S. Extended vertical transatrial
septal approach for the removal of left atrial myxoma.
Ann Thorac Surg 1993; 56: 1216.
23. Vigano M, Grande AM, Gaeta R. Superior transseptal
approach to left atrial myxomas. Ann Thorac Surg
1995; 60: 1860-1861.
24. Guiraudon GM, Ofiesh JG, Kaushik R. Extended vertical
transatrial approach to the mitral valve. Ann Thorac
Surg 1991; 52: 1058-1062.
25. Shinfeld A, Katsumata T, Westaby S. Recurrent cardiac
myxoma: seeding or multifocal disease? Ann Thorac
Surg 1998; 66: 285-288.
26. Zeybek R, Basaran Y, Oztop F. Recurrence of an atrial
myxoma. Int J Cardiol 1991; 33: 435-437.
27. Rankin LI, DeSousa AL. Metastatic atrial myxoma
presenting as intracranial mass. Chest 1978;74:451-452.
28. Budzilovich G, Aleksie S, Greco A, Fernandes J, Harris J,
Finegold M. Malignant cardiac myxoma with cerebral
metastases. Surg Neurol 1979; 11: 461-469.
29. Chen HJ, Liou CW, Chen L. Metastatic atrial myxoma
presenting as intracranial aneurysms with hemorrhage:
case report. Surg Neurol 1993; 40: 61-64.
30. Read RC, White HJ, Murphy ML, Williams D, Sun CN,
Flanagan WH. The malignant potentiality of left atrial
myxoma. J Thorac Cardiovasc Surg 1974; 68: 857-868.
31. Terada Y, Wanibuchi Y, Noguchi M, Mitsui T. Metastatic
atrial myxoma to the skin at 15 years after surgical
resection. Ann Thorac Surg 2000; 69: 283-284.
32. Ng HK, Poon WS. Cardiac myxoma metastasizing to the
brain. Case report. J Neurosurg 1990; 72: 295-298.

Thank you for copying data from http://www.arastirmax.com