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Total protein and fibrinogen variations before and after diethyl carbamazine(dec) treatment in filariasis

Journal Name:

  • Indian Journal of Basic & Applied Medical Research

Publication Year:

  • 2014

Key Words:

Author Name
Abstract (2. Language): 
Lymphatic filariasis is a disableing and disfiguring dieases effecting mankind since antiquity.This infection is prevalent in both urban and rural areas. In the present study effect of diethyl carbamazine before and after treatment for fialariasis has been observerd. We enrolled 48 patients with Micro Filaraemia(MF),50 patients Clinical Filaraemia(CF) and control 52 and counducted study in GGH Kakinada, Andhrapradesh ,India, as Kakinada and its surrounding areas are highly endemic for filareasis . We found there is no significant variations in total protein and fibrinogen levels of patients before and after the treatment of DEC , Hence it can be approved that this drug does not causes damage to the synthatic functions of the liver cells (hepatocytes).There are no reports on the status of serum proteins in filariasis. Hence the present study is under taken to estimate the levels of serum protein and plasma fibrinogen influence in the disease process, and the variations in these parameters before and after DEC treatment.
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