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Comparison of bacterial etiology of non-healing ulcers in diabetic and non- diabetic patients.

Journal Name:

  • Indian Journal of Basic & Applied Medical Research

Publication Year:

  • 2015

Key Words:

Author Name
Abstract (2. Language): 
Introduction: Non-healing ulcers of foot ,particularly indiabetic patients, cause a major medical and economic problem. Diabetes mellitus is not the only cause of non-healing ulcers. There are very few studies where the etiology of non-healing ulcers from non-diabetic patients is studied. We wanted to study, whether there is any difference between such ulcers from diabetic individuals and non-diabetic individuals. Materials & Methods: A total of 86 patients with the non-healing foot ulcers were included in the study. The duration of ulceration was minimum 3-4 weeks which did not respond to conventional therapies. Fifty of them were Diabetic (BSL>200) while other thirty six were non diabetic patients (BSL<200). All the isolates were identified using standard microbiological techniques. Antibiotic sensitivity was tested by Kirby-Bauer disc diffusion technique. Results: out of total 86 samples, growth was obtained in 74 samples (86%). When diabetic and non-diabetic groups were compared, there was a striking difference in the etiology. No growth was seen in 8% of diabetic cases and 22%of non-diabetics. Polymicrobial infections were predominant in diabetic group (52%)than non-diabetic group(25%).Staphylococcus aureus dominated the non-diabetic group as a single isolate from 16 cases (43.2%). In diabetic group, Gram negative bacilli were the main cause on 44 occasions (61%). Conclusion: From the present study we can conclude that the etiology of non-healing ulcers in diabetic patients is different than that of the non-diabetic patients.Giving targeted treatmentafter knowing the causative agent and its drug sensitivity pattern is the best way to treat non-healing ulcers.
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