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İstanbul Kartal bölgesinde okul öncesi çocuklarda asemptomatik A grubu beta hemolitik streptokok taşıyıcılığı

Asymptomatic carriage of group A beta-hemolytic streptococcus among preschool children in Kartal, Istanbul

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DOI: 
doi:10.2399/tahd.08.203
Abstract (2. Language): 
Objective: Group A beta-hemolytic streptococcus (GABHS) is the most common bacterial cause o f acute pharyngitis in children a nd may cause serious complications such as acute rheumatic fever and acute glomerulonephritis. The objective of this study was t o determine the rate of carriage for GABHS among asymptomatic, preschool children w h o apply t o Dr. Lütfi Kırdar Teaching a nd Research Hospital - Family Medicine Outpatient Clinic in Istanbul. Methods: One hundred and fifty children between 3 t o 6 years of age, enrolled in t h e family medicine outpatient clinic f o r other reasons than sore t h r o a t , f r om January t o March 2008, were ran¬ domly and prospectively included in the study. Following history taking and physical examination, swabs of the oropharynx were taken for bacteriological culture and identification. Blood samples were collected and antibodies t o streptolysin O were dedected by latex agglutination tests (ASO). Results: Positive throat cultures t o GABHS were f o u n d in 18 o f 128 patients ( 1 4 . 0 6 % ) and 8 of these ( 4 4 . 4 4 % ) had elevated ASO titers w i t h o u t any proven findings of streptococcal infection. Conclusions: Previous studies demonstrated that the prevalence of GABHS in healthy preschool children was between 2 t o 2 5 . 9 % . Pharyngeal carriage of GABHS of our sample was f o u n d similar w i t h results obtained in t h e western parts o f Turkey.
Abstract (Original Language): 
Amaç: A grubu beta hemolitik streptokok (AGBHS) çocukta akut bakteriye! farenjitin en sık rastlanan etkenidir ve akut romatizmal ateş, akut glomerülonefrit gibi ciddi komplikasyonlara yol açabilir. Bu çalışmanın amacı istanbul Kartal Dr. Lütfi Kırdar Kartal Eğitim ve Araştırma Hastanesi Aile Hekimliği Polikliniği'ne başvuran okul öncesi çocuklarda AGBHS taşıyıcılığı oranını belirlemektir. Yöntem: Ocak-Mart 2008 tarihleri arasında aile hekimliği polikliniğimize boğaz ağrısı dışındaki nedenlerle başvuran üç ila altı yaş arası ardışık 150 çocuk hasta randomize şekilde çalışmaya dâhil edildi. Anamnez ve fizik muayene sonrası bakteri kültürü ve ta¬ nımlama için boğaz sürüntüsü ile antistreptolizin O (ASO) testi için kan örneği alındı. Bulgular: incelenen 128 hastanın 18'inin ( % 1 4 . 0 6 ) boğaz kültürü, AGBHS pozitifti; kültürü pozitif olanların 8'inde ise ( % 4 4 . 4 4 ) herhangi bir s t r e p t o k o k enfeksiyonu bulgusu olmaksızın ASO yük¬ selmesi saptandı. Sonuç: Daha önceki çalışmalarda, sağlıklı okul öncesi çocuklarda % 2 - 2 5 . 9 oranlarında faringeal AGBHS taşıyıcılığı bulunmuştu, çalışmamızdaki AGBHS taşıyıcılığı Türkiye'nin batı yörelerindeki so¬ nuçlarla uyumludur.
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