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Kronik Böbrek Hastalığında Tanı ve Tedavi ile Kardiyovasküler Hastalık ve Risk Faktörlerinin Değerlendirilmesi

Diagnosis and Treatment in Chronic Kidney Disease and Evalution of Cardiovascular Disease and Associated Risk Factors

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Abstract (2. Language): 
Today, chronic kidney disease (CKD) is a world-wide public health problem. Losing kidney function and occurance of cardiovas¬cular disease (CVD) are inevitablely the main clinical outcomes. Increasing evidence suggested that the adverse outcomes of CKD can be prevented or delayed through early detection and treatment. CKD and hypertension are often present together and hypertension is both a cause and a complication of CKD and is a risk factor for progression of kidney disease and for CVD. The goals of antihypertensive therapy in CKD are to lower blood pressure, reduce the risk of CVD, slow progression of CKD and prevent the complications of decreased GFR. A clinical action plan should be developed for each patient, based on the stage of CKD and follow-up intervals for monitoring the patients should be determined by clinical condition.
Abstract (Original Language): 
Günümüzde kronik böbrek hastalığı (KBH) dünya genelinde yaygın bir halk sağlığı problemidir. Böbrek fonksiyonlarının kaybedilmesi ve kardiyovasküler hastalık (KVH) gelişimi kaçınılmaz olarak meydana gelen ana klinik sonuçlardır. Artan kanıtlar KBH'nın kötü sonuçlarının erken tanı ve tedaviyle önlenebileceğini veya geciktirilebileceğini ileri sürmektedir. KBH ve hipertansiyon (HT) sıklıkla birliktedir ve HT, KBH'nın hem nedeni hem de komplikasyonu olup KBH'nın ilerlemesi ve KVH açısından bir risk faktörüdür. KBH'da an-tihipertansif tedavinin amacı kan basıncını düşürmek, KVH riskini azaltmak, KBH'nın ilerlemesini yavaşlatmak ve düşük GFR'nin komplikasyonlarını önlemektir. KBH'nın evresi temelinde her hasta için bir klinik eylem planı geliştirilmelidir ve hastaların takip edilme¬si için takip aralığı klinik duruma göre belirlenmelidir.
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