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Çocuklarda Henoch-Schönlein Purpurası: 50 Olgunun Retrospektif Değerlendirilmesi

Henoch-Schönlein Purpur a in the Children: The evaluation retrospective of 50 patients

Journal Name:

  • Fırat Tıp Dergisi

Publication Year:

  • 2010

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Abstract (2. Language): 
Objective: : Henoch-Schönlein purpura is a systemic vasculitis which mainly affects the children. We aimed to evaluate the epidemiologic and clinical features of the children with diagnosis of Henoch-Schönlein Purpura followed up in our clinic. Materials and Methods: The epidemiological, clinical and laboratory findings, and the data about treatment of all patients with diagnosis of Henoch-Schönlein Purpura were collected by reviewing medical files. Results: 50 children (27 males, 23 females) aged between 1.5-16.5 years included in the study. The mean age of the patients was 7.9±3.6 years. Purpura was the most common finding seen in all patients. The joint involvement and gastrointestinal involvement occurred in 92 % and 62 % of these patients respectively. Renal involvement occurred in 10 patients (20 %), one of them had developed severe nephropathy. The most frequent laboratory abnormalities were leukocytosis (78 %), high erythrocyte sedimentation rate (48 %) and hyper IgA (26 %). Conclusion: Epidemiological and clinical findings of the patients are similar to those in the literature. Although severe nephropathy was found in a small percentage of the children, the prognosis was usually excellent.
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Abstract (Original Language): 
Amaç: Henoch-Schönlein purpurası başlıca çocukları etkileyen sistemik bir vaskülittir. Çalışmada Henoch-Schönlein purpurası tansı ile izlenen çocukları epidemiyolojik ve klinik özelliklerini değerlendirmeyi amaçladık. Gereç ve Yöntemler: Henoch-Schönlein purpurası tanısı alan tüm çocukların epidemiyolojik, klinik, laboratuar bulguları ve tedavi bilgileri dosya kayıtları incelenerek elde edildi. Bulgular Yaşları 1.5 ile 16.5 arasında değişen 50 çocuk çalışmaya dahil edildi. Hastaların ortalama yaşları 7.9±3.6 yıl idi. Hastalarda en sık görülen bulgu purpura idi. Eklem tutulumu ve gastrointestinal tutulum hastalarda % 92 ve % 62 olarak belirlendi. Renal tutulum hastaların 10'nunda (% 20) meydana geldi. Bunların birinde şiddetli böbrek tutulumu oluştu. En sık görülen laboratuar anormalikleri lökositoz (%78), eritrosit sedimantasyon yüksekliği (% 48) ve IgA (% 26) yüksekliği idi. Sonuç: Hastaların epidemiyolojik ve klinik bulguları literatürdekilerle benzerlik gösteriyordu. Şiddetli böbrek tutulumu çocukların küçük bir kısmında olmasına rağmen, prognozu genellikle iyidir.
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  • Turkish

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