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CRYPTOCOCCUS NEOFORMANS’IN VİRÜLENS FAKTÖRLERİ

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Abstract (2. Language): 
Cryptococcus neoformans is an encapsulated fungus and is a significant human pathogen. In this review the current knowledge of host-fungus interactions is discussed and the characteristics it must possess to enter the host and establish progressive disease; such as the polysaccharide capsule, melanin production, mannitol secretion, superoxide dismutase, proteases and phospholipases and it is emphasized the relationship between a study of experimental cryptococcosis done by authors to obtain large encapsulated yeast cells.
Abstract (Original Language): 
Cryptococcus neoformans kapsüllü bir mantar ve önemli bir insan patojenidir. Bu derlemede konak-mantar etkileşimi ile mantarın infeksiyon geliştirmesi için sahip olması gereken ve öncelikle önem kazanan polisakkarit kapsül başta olmak üzere, melanin üretimi, mannitol salgılanması, süperoksit dismutaz, proteaz ve fosfolipazlar gibi karakteristikleriyle ilgili mevcut bilgiler gözden geçirilmiş; yazarlar ın bir kutanöz kriptokokkoz lezyonundan ayırdıkları bir kökenle fare deneyinde kapsülün belirginleştirildiği bir çalışmaları ile ilgi kurulmuştur.
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