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KRONİK HEMODİYALİZ OLGULARINDA HEPATİT C VİRÜS ANTİKOR (ANTİ-HCV AB) SEROKONVERSİYONUNUN UZUN SÜRELİ İZLENMESİ

THE LONG TERM FOLLOW-UP OF SEROCONVERSION RATE OF HEPATİT C VIRUS IN CHRONIC HEMODIALYSIS CASES

Journal Name:

  • Türk Nefroloji, Diyaliz ve Transplantasyon Dergisi

Publication Year:

  • 1998

Key Words:

Keywords (Original Language):

Author NameUniversity of AuthorFaculty of Author
Abstract (2. Language): 
The long term follow-up (1-4 years) of Hepatit C virus seroconversion rate was investigated in chronic hemodialysis cases. Positive seroconversion rate was established 51% for 1 year, 75% for 2 years, 95% for 3 years and 100% for 4 years hemodialysis duration. There was only one negative seroconversion in patients having positive anti-HCV ab during a 4-year-follow-up period. It was established that duration of hemodialysis is a major risk factor for transmission of Hepatit C Virus. As a result, we are of the opinion that, in the determination of transmission sites in hemodialysis centers. the establishment of annual seroconversion rate in long-term follow-up periods is of more realistic data instead ofspot prevalence studies.
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Abstract (Original Language): 
En az 1-4 yıl arasında hemodiyaliz programında olan ve anti-HCVab düzenli olarak izlenen hemodiyaliz olgularında 1-4 yıl içerisindeki serokonversiyon oranlan araştırıldı. 1 yıl takip edilen 47 anti-HCVab negatif olgunun 23'ünde (%51), 2 yıl takip edilen 33 anti-HCVab negatif olgunun 25'inde (%75), 3 yıl takip edilen 21 anti-HCVab negatif olgunun 32'inde (%95) ve 4 yıl takip edilen 21 anti-HCV olgunun tamamında (%100) pozitif serokonversiyon saptandı. 4 yıl içerisinde anti-HCVab pozitif olgulardan yalnızca l'inde negatif serokonversiyon gözlendi. HCV bulaşında hemodiyaliz süresinin önemli bir risk faktörü olduğu saptandı. Sonuç olarak, diyaliz merkezlerinin HCV bulaşmdaki yerlerinin belirlenmesinde spot prevelans çalışmaları yerine uzun süreli takiplerde yıllık serokonversiyon oranlarının saptanmasının daha gerçekçi veriler sağlayabileceği kanısına varıldı.
FULL TEXT (PDF): 
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  • 1
21-23
  • Turkish

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