You are here

Home » Content

Deneysel barsak strangulasyonu sonrası kanda ve periton sıvısında laktik asit değerleri

Lactic acid values at blood and peritoneal fluid after experimental bowel strangulation

Journal Name:

  • İnönü Üniversitesi Tıp Fakültesi Dergisi

Publication Year:

  • 1994

Key Words:

Keywords (Original Language):

Author Name
Abstract (2. Language): 
Sometimes it is difficult to diagnose bowel strangulation on time and operate early. Delay at the surgical inter/ere raises the mortality rate. Difficulty of clinical early diagnosis made the surgeons look for the changes of some parameters at blood and peritoneal fluid as an aid. At our experimental study we made bowel strangulation model and determined the values of lactic acid, ammonia and LDH at blood and peritoneal fluid for the period of 24 hours. We also determined the same values at a simple bowel destruction model. According to the results, we found significant changes at the lactic acid values of blood and peritoneal fluid. Since the peritoneal fluid values are more specific we advise the determination of peritoneal lactic acid values as an aid for the early clinical diagnosis of bowel strangulation. /Journal of Turgut Özal Medical Center l<2):83-8~. 1994/
Bookmark/Search this post with
Abstract (Original Language): 
Akut batın nedenleri arasında yer alan barsak strangülasyonunun tanısını zamanında koyarak erken cerrahı müdahalede bulunulması bazen zor olmakta ve gecikilmesi durumunda mortalite çok artmaktadır. Barsak strangulasyonunda klinik tanı zorluğu cerrahları kanda ve peritoneal sıvıda yardımcı olucu parametre/erdeki değişiklikleri araştırmaya itmiştir. Bu deneysel çalışmamızda oluşturduğumuz barsak strangulasyonu modelinde 24 saat boyunca kanda ve periton sıvısında laktik asit, amonyum ve LDH seviyelerini araştırdık. Aynı teshilleri basit barsak tıkanması modelinde yaptık. Aldığımız verilere göre periton sıvısında ve kanda laktik asit seviyelerinde dikkate değer yükselmeler oldu. Periton sıvısındaki yükselmenin daha spesifik olması nedeniyle, barsak strangulasyonundan şüphelenilen vakalarda abdominal parasentez ile laktik asit seviyesinin takibini öneriyoruz. [Turgut Özal Tıp Merkezi Dergisi 1(2): 83-87, 1994J
FULL TEXT (PDF): 
PDF icon arastirmax-deneysel-barsak-strangulasyonu-sonrasi-kanda-periton-sivisinda-laktik-asit-degerleri.pdf
  • 2
83-87
  • Turkish

REFERENCES

References: 

1. Sarr MG, Burkley GB, et al. Preoperative recognition of intestinal strangulation obtruction Am J Surgery 1983; 145: 176-81.
2. Mansberger AR. Value of peritoneal fluid ammonia levels in the differential diagnosis of the acute abdomen. Ann Surg 1962; 155: 998-1010.
3. Mansberger AR. Peritoneal ammonia levels in acute intra-abdominal disease: a reapraisal. Am J Surg 1967; 113. 37-43.
4. Rush BJ, Host WR, et al. Intestinal ischemia and some organic substances in serum and abdominal fluid. Arch Surgery 1972; 105: 151-6.
5. Sarr MG. Mechanical small bowel obstruction. In: Shacklefand RT, Zuidema GD, eds. Surgery of the Alimentary Tract. Philadelphia. WB Saunders 1986: 455-9.
6. Stewandson RH, Nyhus LM. Critical operative management of small bowel obstruction. Ann Surgery 1978;187:189-93.
7 Bızer LS. Lieblmg RW. et al. Small bowel obstruction Surgery 1981:89.407-13.
8 Taylor BM, Janiieson WG, et al. Preinfarction diagnosis of acute mesenteric ischemia by simple measurement of inorganic phosphate in body fluids. Can J Surgery 1979;22:40-5.
9 Jamieson VVG. Taylor BM, et al. The significance of urine phosphat measurements in the early diagnosis of intestinal infarction. Surg Gynecol Obstet 1979;148:334-8
10 Greaber GM. Cafferty PJ, et al. Changes in serum total creatinine phosphokinase and its
isoenzymes caused by experimental ligation of the superior mesenteric artery. Ann Surgery 1981; 193: 499-505.
11 Mansberger AR, Cawley RA, et al. The origin and utilization of ammonia in strangulation obstruction of the small bowel Ann Surgery 1959; 150:880-9.
12. Large H. Differential diagnostic significance of lactate in acute abdominal diseases. Chirurg 1989;60 (5):356-60.
13. Murray MJ, Barbase JJ, et al. Serum D(-)- lactate levels as a peridictor of acute intestinal ischemia in a rat model. J Surg Res 1993;54(5):507-9.

Thank you for copying data from http://www.arastirmax.com