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"Quorum sensing": mikroorganizmalar iletişim mi kuruyor?

"Quorum sensing": Do the microorganisms communicate?

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Abstract (2. Language): 
Many Gram positive and negative bacteria, and fungi communicate with each other by means of different signal molecules. As well as releasing the signalling molecules, microbes are also able to measure the concentration of the molecules in their environment as a clue of the number of microbial population. By this way, they behave in a well-coordinated manner, regulate their virulence factors in order to escape from the immune response of the host and establish a successful infection process. In this respect, if we can block the quorum sensing systems (signaling pathways) we may be able to prevent development of an infection, to produce new, safer and more powerful antibiotics.
Abstract (Original Language): 
Birçok Gram pozitif ve negatif bakteri ve mantarlar birbirleri ile farklı sinyal molekülleri aracılığıyla iletişim kurmaktadır. Bu sinyal moleküllerini üretmekle birlikte, mikroorganizmalar bu moleküllerin konsantrasyonunu ölçerek çevrelerindeki mikrobiyal topluluğun miktarı hakkında da bilgi sahibi olmaktadır. Böylece iyi koordine olmuş bir davranış sergilemekte, konağın immün yanıtından kaçabilmek için virülans faktörlerini regüle etmekte ve başarılı bir enfeksiyon süreci geliştirmektedir. Bu bağlamda, eğer "Quorum Sensing" sistemi (sinyal yolakları) bloke edilebilirse enfeksiyon gelişimi önlenebilecek, yeni, daha güvenli ve güçlü antibiyotikler üretilebilecektir.
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