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KUPFFER HÜCRESİ

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Abstract (2. Language): 
Kupffer cells were firstly described by von Kupffer at 1876. In our work we reviewed the function and properties of these cells especially other than fagocytosis whom are cell-cell communication and some clinical importances of these features. Histologic and cell origin properties were also mentioned. Also the effect of donor liver Kupffer cells is stressed for organ transplantation.
Abstract (Original Language): 
Bu çalışmada, ilk kez 1876 yılında von Kupffer tarafından tanımlanan Kupffer hücrelerinin, bilinen fagositik özellikleri yanı sıra özellikle hepatositler ile olan hücrelerarası haberleşme mekanizmaları, hücrelerarası etkileşimleri ve bu etkileşimlerin klinik açıdan önemli sonuçları üzerinde durulmuş, bazı histolojik özellikleri, karaciğerdeki yerleşimleri, köken ve işlevleri hakkında ayrıntılı bilgi verilmiştir. Karaciğer organ naklinde, vericinin Kupffer hücrelerinin erken doku ret reaksiyonundaki önemli yeri anlatılmıştır.
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