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ANTIULCER ACTIVITY OF SHARK LIVER OIL ON ASPIRIN INDUCED GASTRIC ULCER IN RATS

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Abstract (2. Language): 
Shark liver oil is one of the sources of cellular energy and provides repair and restoration of damaged cells, and supports in protection of the body from the emergence of tumorous conditions. The Shark liver oil was tested orally at the dose of 1gm/kg/oral body weight, on gastric ulceration experimentally induced by Aspirin. The parameters considered to assess the Antiulcer activity were percentage of ulcer, ulcer index, percentage of inhibition, pH, free acidity and total acidity. Pretreatment with the Shark liver oil resulted in significant decrease of the ulcerated area and reduced pH, free acidity and total acidity.
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REFERENCES

References: 

1. M. Umamaheswari, K. Ashokkumar, R. Rathidevi, A.
T. Sivashanmugam, V. Subhadradevi and T. K. Ravi.
Antiulcer and in vitro antioxidant activities of
Jasminium grandiflorum L., J Ethnopharmacol, 110
464 (2007).
2. S. L. Bodhankar and N. S. Vyawahare, A textbook of
Pathophysiology, 2nd ed. Pune, Nirali prakashan,
2005, pp 6.1-6.6.
3. http://www.vitadigest.com Shark squalene (shark
liver oil) from VitaDigest, Walnut CA 91789 [online]
(2009).
4. Shark oil monograph from Natural medicines
comprehensive data base. Scientific Gold Standard
for Evidence-Based clinical information on natural
medicines. Therapeutic research faculty, Stockton:
CA 95208; Nov 20, (2009).
5. http//:www.pdrhealth.com/drug_info/nmdrugspro
files/nutsupdrugs/squ_0240.shtm
6. N. Solomon, R. Passwater, I. Joelssun, L. Haimes.
Shark liver oil, Nature’s Amazing Healer. Kensington
books, 1997.
7. Biological actions and Clinical applications of Shark
liver oil. Pol Merkur Lekarskj-2006 [PUBMED].
8. C. Riber, M. Wojdemann, T. Bisgaard, H. Ingels, J. F.
Rehfeld, O. Oslen. Fish oil reduces gastric acid
secretion, Scand J Gastroenterol 34: 845 (1999).
9. M. A. Al-Meshal, K. M. Lutfi, M. Tariq. Cod liver oil
inhibits Indomethacin induced gastropathy without
affecting its bioavailability and pharmacological
activity, Life Science 48: 1401 (1991).
10. A. Azamthulla, M. Asad, P. V. Satya. Antiulcer activity
of Allium Sativum bulb juice in rats, Saudi Pharm J
17: 70 (2009).
11. H. G. Vogel, W. H. Vogel, B. A. Scholkens, J. Sandow,
W. F. Vogel. Drug Discovery and Evaluation of
Pharmacological Assays, 2nd Ed, New York,
Springer-Verlag Berlin Heidelberg, 2002 pp. 870.
12. I. M. Gajjar. Chemical composition of shark liver oil, J
Sci Ind Res 5: 18 (1946).
13. K. Akutsu, Y. Tanaka, K. Hayakawa. Occurrence of
poly brominated diphenyl ethers and
polychlorinated biphenyls in Shark liver oil
supplements, Food Addit Contam 23: 1323 (2006).
14. P. T. Pugliese, K. Jordan, H. Cederberg, J. Brohult.
Some biological actions of alkoxyglycerols from
Shark liver oil, J Altern Complement Med. 4: 8799
(1988).

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