You are here

HEMODÎALÎZ HASTALARINDA TRANSPLANT ÖNCESİ VE SONRASI SOL VENTRİKÜL FONKSİYONLARININ DEĞERLENDİRİLMESİ

Share
EVALUATION OF LEFT VENTRICULAR FUNCTION IN HEMODIALYSIS PATIENTS AFTER RENAL TRANSPLANTATION

Journal Name:

FULL TEXT (PDF): 

Volume:

Publication Year:

Number:

Sayfa Aralığı:: 
115-118

Publication Language:

Abstract (Original Language): 
Hemodiyaliz hastalarında, kardiyakfonksiyonları etkileyen birçok faktör (hipertansiyon, anemi, A-V fis-tül, hiperparatiroidizm, hiperhidratasyon, elektrolit imbalansı, üremik toksinler) bulunmaktadır. Bu çalış¬mada böbrek transplantasyonu yapılan 11 hastanın transplant öncesi ve sonrası ekokardiyografik bulgu¬ları değerlendirilmiş, elde edilen bulgular 11 sağlıklı kişiden oluşan kontrol grubu ile karşılaştı/itmiştir. Hastaların yaşları 24-62 arasında değişmekte olup, yaş ortalaması 39.64 ± 3.92, böbrek greft yaşamı 27.73 ±4.01 aydır (12-49). Ekokardiyografik değer¬lendirmede transplant öncesi/sonrası sol ventrikül sis-tolsonu çapı 32.1129.8 mm (p>0.05), sol ventrikül di-astol sonu çapı, transplant öncesi/sonrası 48.0147.4 mm (p>0.05) bulunurken, ejeksiyonfraksiyonu, transplant öncesi/sonrası % 64.181 % 66.27(p>0.05) ola¬rak değerlendirilmiştir. Bu değerler kontrol grubun¬daki değerlerle karşdaşlırıldığında anlamlı derecede düşük bulunmuştur (p<0.05). Sonuç olarak hemodia-liz hastalarının miyokardiyumunda anatomik olarak ciddi, kalıcı değişiklikler gelişmekte ve böbrek trans¬plantasyonu ile bu değişiklikler ortadan kaldırılama-maktadır.
Abstract (2. Language): 
There are many factors (hypertension, anemia, hyperparathyroidism, AV fistula, hyperhydration electrolyte imbalance, uremic toxins) which affect the cardiac functions of hemodialysis patients. In this study 11 patients who received renal transplantation were evaluated echocardiographycally and results were compared with the echocardiographic findings of 11 healthy subjects. The age of patients ranged from 24 to 62 years (mean age was 39.6 ± 3.9 years), renal graft survival was 27.7 ± 4.0 months (1222 to 49 months). Before and after the transplantation the left ventricle end systolic diameter was measured ec-hocardiographycally as 32.1129.8 mm. respectively (p>0.05), end diastolic diameter was measured as 48.0147.4 mm. respectively (p>0.05), ejection fraction was 64.18 % I 65.27 % respectively (p>0.05). These values were significantly lower than the control valu¬es (p<0.05). As a result, myocardium of hemodialysis patients is subjected to important anatomical changes and renal transplantation does not totally correct this situation.

Keywords (Original Language):

REFERENCES

References: 

1. Kramer W, Wi/cmann V, Thormann J. Kindlcr M, Mueller K, Schlepper M. Cardiac dysfunction in patients otl maintenance hemodialysis. Contrib Nepiırol I9N6, 52: 97-107.
2. Hüling J, Kramer W, Schullerle S, Wi/.einann V. Analy SİS of lel'l ventricular changes associated with chronic hemodialysis. Nephron 1988; 49: 284-290.
3. Lanke/ L. Lowed J. Sabbaga LT. Uremic myocanhn pathy. Nephron 1975. 15: I7-2S.
4. Kramer W, Wiseman V. Canemlem G. et al. Cardiac dysfunction in patients on inaintaince hemodialysis. Systolic and diastolic properties of the left venliicle as scssed by invasive method. Contr Nephrol 19HİC, 52 110 124.
5. I9KX hunt National Coıııınille: The 19KX Kepoil m ıhı Joint National C inniillee on Detect too. Evaluation n Treatment bf High Stood Pressure. Arch In.cm NK«< I'JN.S; I4X: It 2> IU2l>.
6. Kuecherer HE Kee LL, Modin G, Cheitlin MD, Schiller NB. Echocardiography in serial evaluation of left ventricular systolic and diastolic function: Importance of image acquisition, quantitation, and physiologic applications. J Am Soc Echocardiogr 1991; 4: 203-208.
7. Techholz LE, Kreulen T, Herman MV, Gorlin R. Prob¬lems in echocardiography volume determinations: Ec-hocardiographic - angiographic correlations in the pre¬sence or absence of asynergy. Am J Cardiol 1976; 37: 7¬11.
8. Troy BL, Pompo J, Rakley CE. Measurement of left ventriculer wall thickness and mass by echocardiograp-hy Circulation 1972; 45: 602-607.
9. Rainc AEG. Hypertension and the kidney. Br Med Bull 1994;50:322-341.
10. Luke RG. Hypertension in renal transplant recipients. Kidney Int 1987; 31: 1024-1037.
11. Teruel JL, Rodriges R, Quereda C, Yuste P, Marccn R, Ortuno 'ARegression of left ventricular hypertrophy af¬ter rena; transplantation. Transplantation 1987; 43: 307¬309.
12. Van Ypersele de Strihou E, Vereerstraeten P, Wauthier M et al. In: H Hamburger, H Crosnier, J Grunfield, (eds.) Advances in Nephrology. Year Book Medical, Chicago 1983; 12; pp 41-60.
13. Curtis JJ, Luke RG, Dictheim AG, Whelchel JD, Jones
P. Benefits of removal of native kidneys in hypertension after renal transplantation. Lancet 1985: ii: 739-742.
14. Hricik DE, Mayes JT, Schulak JA. Independent effects of cyclosporine and prednisolone on posttransplant hypercholesterolemia. Am J Kidney Dis 1991; 18: 353.
15. Deray G, Benhmida M, Le Hoang P et al. Renal functi¬on and blood pressure in patients receiving long-term, low-dose cyclosporine therapy for idiopathic autoimmu¬ne uveitis. Ann Intern-Med 1992; 117: 578-583.
16. Fujimoto S, Kagoshima T, Hashimoto T, Nakajima T, Dohi K. Left ventricular diastolic function in patients on maintenance hemodialysis: comparison with hyper lensi -eve heart disease and hypertrophic cardiomyopathy.
Clin Nephrol 1994; 42: 109-116.
17. Morales MA, Fcrdeghini EM. Pizzarelli F, et al. Structu¬ral abnormalities of left ventricular myocardium in pati¬ents under chronic hemodialysis. Nephrol Dial Trans¬plant (Abst.) 1992 Annu i! FDTA ERA Congress, Vien¬na.
18. Montague TJ, MacDonald RPR, Bout, !:E. Maclead
AJ- Cohen AD, Smilh E. Cardiac function ii end-stage
renal disease. Chest 1982; 82:441-445. '
19. Ritz E, Deppisch R, Stier E, Hönsch G. Atherogenesis and cardiac death arc they related to dialysis procedure and biocompatibility ? Nephrol Dial Transplant 9 (suppl
2): 1994; 165-172.
20. Amann K, Mall G, Ritz E. Myocardial interstitial fibro-sis in uremia: is it relevant ? Nephrol Dial Transplant
1994; 9: 127-128.
21. Mall G, Huther W, Schneider J, Lundin P, Ritz E. Diffu¬se intermyocardiocytic fibrosis in uracmic patients.
Nephrol Dial Transplant 1990; 5: 39-44.
22. Chatty Me, Dcodhar SD. Myocardial changes and kid¬ney transplantation. Arch Pathol 1969; 88: 602-608.
18

Thank you for copying data from http://www.arastirmax.com