Preoperatif Yüksek C-Reaktif Protein Seviyesi Kardiyak Cerrahi Sonrası İnfeksiyonu Yansıtır mı?

Makalenin İngilizce İsmi: 
Does preoperative high level C-reactive protein reflect infection after cardiac surgery?
Makale İçerik Bilgileri
Makale Dili: 
Türkçe
Anahtar Kelimeler: 
Açık kalp cerrahisi
C-reaktif protein
infeksiyon
Türkçe Özet: 

Amaç: C- reaktif protein (CRP), inflamasyon veya doku hasarı sonrasında en hızlı yükselen ve iyileşme süresinde en hızlı düşen akut faz proteinidir,
preoperatif CRP düzeyinin ölçümü, kalp cerrahisi sonrası infeksiyon gelişme riski olan hastaları belirlemek için kullanılabilir.
Yöntem: Dr. Siyami Ersek Hastanesinde Ocak 2001-Mayıs 2001 arasında açık kalp cerrahisi yapılan ardışık 30 hasta prospektif olarak de-
ğerlendirmeye alındı. Sürekli ateş takibi yapılan hastaların preoperatif, postoperatif 1.gün, 4. gün, 6. gün CRP değerlerine bakıldı. CRP immünoturbidimetrikal
yöntemlerle bakıldı ve normal değeri 5mg/l ve altı olarak kabul edildi.
Bulgular: Postoperatif dönemde infeksiyon gelişen grubun preoperatif CRP değerlerinin (23.21±6.98), infeksiyon gelişmeyen gruptan
(5.21±1.41) yüksek olduğunu gördük (p<0.001). 2 hastada yüzeyel yara yeri infeksiyonu, 3 hastada idrar yolu enfksiyonu, 1 hastada pnömoni
görüldü. Hastaların hiçbirinde ölüm görülmedi.
Sonuç: Preoperatif CRP değerlerinin ölçümü, operasyon sonrası gelişebilecek mortalite ve morbiditenin önceden önlem alınmasına katkıda
bulunabileceğini gözönünde bulundurmak gerekir.

Key Words: 
Open cardiac surgery; C-reactive protein; infection
İngilizce Özet: 

Objectives: C-reactive protein (CRP) is an acute phase protein which increases the fastest after inflammation or tissue injury and which
decreases the fastest during recovery period. The measurement of the preoperative CRP level can be used for determining the risk for development
of infection following cardiac surgery.
Methods: Thirty consecutive patients who had open cardiac surgery between January 2001 and May 2001 at Dr. Siyami Ersek Hospital were
evaluated. The CRP levels of the patients whose temperature being followed up were measured preoperatively and in postoperative days 1,
4 and 6. The normal level for CRP was accepted to be 5 mg/l or less.
Results: We concluded that the preoperative CRP levels in the group who had infection postoperatively were higher than the group without
infection (23.21±6.98 vs 5.21±1.41). Two patients had superficial wound infection, 3 had urinary tract infection and 1 had pneumonia. No
death was detected.
Conclusion: It should be taken into account that the measurement of the preoperative CRP levels can contribute to prevent postoperative
mortality and morbidity that might progress after surgery beforehand.

Yazar Bilgileri
1. Yazar
Yazar Adı: 
Süheyla Keser
2. Yazar
Yazar Adı: 
Önder Teskin
Yazar Ünvanı: 
Doktor
Yazar E-posta: 
oteskin@hotmail.com
3. Yazar
Yazar Adı: 
Taner İyigün
4. Yazar
Yazar Adı: 
Ufuk Çiloğlu
5. Yazar
Yazar Adı: 
Batuhan Özay
6. Yazar
Yazar Adı: 
Gürkan Kömürcü
7. Yazar
Yazar Adı: 
Cem Arıtürk
8. Yazar
Yazar Adı: 
Sabri Dağsalı
Makale Künye Bilgisi
Makalenin Yayımlandığı Dergi: 
Cerrahpaşa Tıp Dergisi
Makale Yayın Yılı: 
2008
Cilt/Sayı: 
39
Sayı: 
4
Sayfa Aralığı: 
144-149
PDF Dosyası: 
application/pdf iconarastirmax_980_pp_144-149.pdf
Makalenin Yayınlandığı Web Sitesindeki Linki: 
Makaleyi Dergi Web Sitesinden İndirin
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