Gebelik ve Tiroid Hastalıkları Olgularının Değerlendirilmesi

Makalenin İngilizce İsmi: 
Evaluation of cases with pregnancy complicated by thyroid diseases
Makale İçerik Bilgileri
Makale Dili: 
Türkçe
Anahtar Kelimeler: 
Gebelik
Hipotiroidi
hipertiroidi
perinatal mortalite ve morbidite
Key Words: 
Pregnancy
Hyperthyroidism
hypothyroidism
perinatal mortality and morbidity
İngilizce Özet: 

To evaluate the outcomes of the pregnancies complicated by thyroid diseases treated at our clinic and to review the current
literature. A total of 117 pregnancies complicated by thyroid diseases treated in our clinic were investigated retrospectively. Free
T4 and TSH levels were assessed as thyroid function tests. While thyroid peroxidase and anti-thyroglobulin antibody levels were
studied for Hashimoto’s thyroiditis, thyroid stimulating antibodies were evaluated for Graves’ disease. Cases with hypothyroidism
were managed by thyroid hormone replacement therapy whereas propylthiouracyl was the drug of choice in patients who suffered
hyperthroidism. Out of the 117 pregnant women with thyroid diseases included in the study, 85 had hypothyroidism and 32 had
hyperthyroidism. The etiology of hypothyroidism was found to be Hashimoto’s thyroiditis in 24.7 %, iodine deficiency in 30.6 %
and thyroidectomy in 44.7 %. In cases with hypothyroidism the rates of intrauterine growth retardation, preterm delivery, preeclampsia
and gestational diabetes mellitus were 4.7, 7.1, 3.5 and 9.4 % respectively. In 40 % of the pregnant women with hypothyroidism,
the dose of the thyroid replacment therapy has increased and no problems were recorded in the newborns. Among
the cases with hyperthyroidism and pregnancy, 78.1 % had Graves’ disease and 21.9 % had hyperactive thyroid nodules. In hyperthyroidism
patients, the rates of intrauterine growth retardation, preterm labor, preeclampsia and gestational diabetes were 6.2,
12.5, 9.3 and 6.3 % respectively. The fetuses and the newborns had no significant problems. The undesired consequences of the
thryoid diseases for both the fetus and the mother can be prevented by the cooperative intervention of the experienced obstetricians
and endocrinologists.

Makale Künye Bilgisi
Sayı: 
1
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Makalenin Yayınlandığı Web Sitesindeki Linki: 
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Referanslar: 

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